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Human Identification: The Use of DNA Markers

  • Book
  • © 1995

Overview

Editors:
  1. Bruce S. Weir
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Part of the book series: Contemporary Issues in Genetics and Evolution (CIGE, volume 4)

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-v
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  2. Introduction

    • B. S. Weir
    Pages 1-2

  3. A method for quantifying differentiation between populations at multi-allelic loci and its implications for investigating identity and paternity

    • David J. Balding, Richard A. Nichols
    Pages 3-12

  4. The effect of relatedness on likelihood ratios and the use of conservative estimates

    • John F. Y. Brookfield
    Pages 13-19

  5. The effects of inbreeding on DNA profile frequency estimates using PCR-based loci

    • Bruce Budowle
    Pages 21-25

  6. Correlation of DNA fragment sizes within loci in the presence of non-detectable alleles

    • Ranajit Chakraborty, Zhaojue Li
    Pages 27-36

  7. Inference of population subdivision from the VNTR distributions of New Zealanders

    • Andrew G. Clark, J. Frances Hamilton, Geoffrey K. Chambers
    Pages 37-49

  8. Conditioning on the number of bands in interpreting matches of multilocus DNA profiles

    • R. N. Curnow
    Pages 51-53

  9. Match probability calculations for multi-locus DNA profiles

    • Peter Donnelly
    Pages 55-67

  10. Population genetics of short tandem repeat (STR) loci

    • Peter Gill, Ian Evett
    Pages 69-87

  11. Assessing probability of paternity and the product rule in DNA systems

    • David W. Gjertson, Jeffrey W. Morris
    Pages 89-98

  12. The forensic debut of the NRC’s DNA report: population structure, ceiling frequencies and the need for numbers

    • D. H. Kaye
    Pages 99-105

  13. Applications of the Dirichlet distribution to forensic match probabilities

    • Kenneth Lange
    Pages 107-117

  14. The honest scientist’s guide to DNA evidence

    • Bruce S. Weir
    Pages 119-124

  15. A comparison of tests for independence in the FBI RFLP data bases

    • P. J. Maiste, B. S. Weir
    Pages 125-138

  16. Alternative approaches to population structure

    • Newton E. Morton
    Pages 139-144

  17. DNA evidence: wrong answers or wrong questions?

    • Bernard Robertson, G. A. Vignaux
    Pages 145-152

  18. Subjective interpretation, laboratory error and the value of forensic DNA evidence: three case studies

    • William C. Thompson
    Pages 153-168

  19. Exact tests for association between alleles at arbitrary numbers of loci

    • D. Zaykin, L. Zhivotovsky, B. S. Weir
    Pages 169-178

  20. A bibliography for the use of DNA in human identification

    • B. S. Weir
    Pages 179-213
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Keywords

About this book

The ongoing debate on the use of DNA profiles to identify perpetrators in criminal investigations or fathers in paternity disputes has too often been conducted with no regard to sound statistical, genetic or legal reasoning. The contributors to Human Identification: The Use of DNA Markers all have considerable experience in forensic science, statistical genetics or jurimetrics, and many of them have had to explain the scientific issues involved in using DNA profiles to judges and juries. Although the authors hold differing views on some of the issues, they have all produced accounts which pay due attention to the, sometimes troubling, issues of independence of components of the profiles and of population substructures. The book presents the considerable evolution of ideas that has occurred since the 1992 Report of the National Research Council of the U.S.
Audience: Indispensable to forensic scientists, laying out the concepts to all those with an interest in the use of genetic information. The chapters and exhaustive bibliography are vital information for all lawyers who must prosecute or defend DNA cases, and to judges trying such cases.

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