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Insect Cell Cultures

Fundamental and Applied Aspects

  • Book
  • © 2002

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Editors:
  1. J.M. Vlak

    1. Dept. of Virology, Wageningen Agricultural University, The Netherlands

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  2. C.D. Gooijer

    1. Dept. of Food Science, Wageningen Agricultural University, The Netherlands

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  3. J. Tramper

    1. Dept. of Food Science, Wageningen Agricultural University, The Netherlands

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  4. H.G. Miltenburger

    1. Dept. of Zoology, Technical University, Darmstadt, Germany

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Part of the book series: Current Applications of Cell Culture Engineering (CACC, volume 2)

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Table of contents (27 chapters)

  1. Front Matter

    Pages ii-vii
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  2. Insect Cell Lines

    1. Development and characterization of insect cell lines

      • Dwight E. Lynn
      Pages 3-11

    2. New approaches to insect tissue culture

      • Danica Baines
      Pages 13-22

    3. Transgenic insect cells: mosquito cell mutants and the dihydrofolate reductase gene

      • Ann Marie Fallon
      Pages 23-31

    4. Insect cell physiology

      • Ravinder Bhatia, Gary Jesionowski, Jerome Ferrance, Mohammad M. Ataai
      Pages 33-41

    5. Insect cell cultivation: growth and kinetics

      • Georg Schmid
      Pages 43-56

    6. Medium design for insect cell culture

      • Ernst-Jürgen Schlaeger
      Pages 57-70

  3. Viruses

    1. Baculovirus-insect cell interactions

      • Gary W. Blissard
      Pages 73-93

    2. Replication patterns and cytopathology of cells infected with baculoviruses

      • Greg V. Williams, Peter Faulkner
      Pages 95-110

    3. Construction of baculovirus recombinants

      • Paul A. Kitts
      Pages 111-123

    4. Passage effect of virus infection in insect cells

      • Peter J. Krell
      Pages 125-137

    5. Post-translational modifications in insect cells

      • Hans-Dieter Klenk
      Pages 139-144

    6. Productivity of insect cells for recombinant proteins

      • James E. Maruniak
      Pages 145-148

    7. Chaperone and foldase coexpression in the baculovirus-insect cell expression system

      • Michael J. Betenbaugh, Eric Ailor, Erik Whiteley, Paul Hinderliter, Tsu-An Hsu
      Pages 149-159

  4. Engineering Aspects

    1. Shear sensitivity of insect cells

      • Jeffrey J. Chalmers
      Pages 163-171

    2. Insect cell bioreactors

      • Spiros N. Agathos
      Pages 173-189

    3. Perfusion bioreactors for the production of recombinant proteins in insect cells

      • Volker Jäger
      Pages 191-198

    4. Immobilization of insect cells

      • Jian-Yong Wu, Mattheus F. A. Goosen
      Pages 199-208

    5. Modelling baculovirus infection of insect cells in culture

      • John Francis Power, Lars Keld Nielsen
      Pages 209-219

    6. Scale up aspects of sparged insect-cell bioreactors

      • J. Tramper, J.M. Vlak, C.D. de Gooijer
      Pages 221-229
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Keywords

Reviews

`In summary, this book covers a wide range of aspects relating to insect cell culture and the baculovirus expression system. It is an authoritative volume which is clearly and conci8sely written by experts selected from industry and academia and is to be highly recommended.'
Entomologia Experimentalis et Applicata, 87 (1998)
`This is an authoritative reference text written by leading experts in their respective fields of insects cell culture. The book targets a potential audience ranging from students and researchers in academia through to those concerned in industry with biotechnology applications.'
SGM Quarterly, August (1997)

Editors and Affiliations

  • Dept. of Virology, Wageningen Agricultural University, The Netherlands

    J.M. Vlak

  • Dept. of Food Science, Wageningen Agricultural University, The Netherlands

    C.D. Gooijer, J. Tramper

  • Dept. of Zoology, Technical University, Darmstadt, Germany

    H.G. Miltenburger

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