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Nitric Oxide and Infection

  • Book
  • © 2002

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Editors:
  1. Ferric C. Fang

    1. University of Colorado Health Sciences Center, Denver

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Table of contents (23 chapters)

  1. Front Matter

    Pages i-xxv
    Download chapter PDF

  2. Introduction

    1. An Overview of Nitric Oxide in Infection

      • Ferric C. Fang
      Pages 3-9

  3. Historical Aspects of Nitric Oxide

    1. The Discovery of the Biological Synthesis of Nitric Oxide

      • Jonh B. Hibbs Jr., Neil R. Bastian
      Pages 13-33

  4. Biological Roles of Nitric Oxide

    1. Biochemistry of Nitric Oxide

      • Benjamin Gaston, Jonathan S. Stamler
      Pages 37-55

    2. Enzymology of Nitric Oxide Biosynthesis

      • Benjamin Hemmens, Bernd Mayer
      Pages 57-76

    3. Cytokine Regulation of Nitric Oxide Production

      • Heiko Mühl, Charles A. Dinarello
      Pages 77-94

    4. Human Mononuclear Phagocyte Nitric Oxide Production and Inducible Nitric Oxide Synthase Expression

      • J. Brice Weinberg
      Pages 95-150

    5. Cardiovascular Actions of Nitric Oxide

      • Daryl D. Rees
      Pages 151-174

    6. Biochemical Regulation of Nitric Oxide Cytotoxicity

      • Andrew J. Gow, Raymond Foust III, STuart Malcolm, Madhura Gole, Harry Ischiropoulos
      Pages 175-187

    7. Cytoprotective Effects of NO against Oxidative Injury

      • David A. Wink, Yoram Vodovotz, Willliam DeGraff, John A. Cook, Roberto Pacelli, Murali Krishna et al.
      Pages 189-198

    8. Immunomodulatory Actions of Nitric Oxide

      • Iain B. McInnes, Foo Y. Liew
      Pages 199-213

    9. Nitric Oxide and Epithelial Host Defense

      • Nigel Benjamin, Roelf Dykhuizen
      Pages 215-230

    10. Antimicrobial Properties of Nitric Oxide

      • Mary Ann DeGroote, Ferric C. Fang
      Pages 231-261

  5. Nitric Oxide in Specific Infections

    1. Nitric Oxide in Sepsis

      • Gillian Wray, Christoph Thiemermann
      Pages 265-280

    2. Nitric Oxide in Mycobacterium tuberculosis Infection

      • John Chan, Janne Flynn
      Pages 281-307

    3. Nitric Oxide in Malaria

      • Nicholas M. Anstey, J. Brice Weinberg, Donald L. Granger
      Pages 311-341

    4. Nitric Oxide in Schistosomiasis

      • Isabelle P. Oswald
      Pages 343-360

    5. Nitric Oxide in Leishmaniasis

      • Christian Bogdan, Martin Röllinghoff, Andreas Diefenbach
      Pages 361-377

    6. Nitric Oxide in Viral Myocarditis

      • Charles J. Lowenstein, Marta Saura, Carlos Zaragoza
      Pages 379-396

    7. Nitric Oxide in Influenza

      • Takaaki Akaike, Hiroshi Maeda
      Pages 397-415
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Keywords

About this book

Familiarity with nitric oxide is essential to a modern understanding of pathophysiologic mechanisms of infectious disease. Recent research has established nitric oxide and related reactive nitrogen intermediates to be important molecular mediators of diverse physiologic processes such as control of vascular tone, regulation of the immune system, and microbial and tumor cell growth. This book contains chapters by the leading researchers in the field and examines the biology and biochemistry of nitric oxide and its role in a variety of specific infections ranging from sepsis, tuberculosis and malaria to viral myocarditis, influenza, and AIDS.

Editors and Affiliations

  • University of Colorado Health Sciences Center, Denver

    Ferric C. Fang

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