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Growth Factors, Peptides, and Receptors

  • Book
  • © 1993

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Editors:
  1. Terry W. Moody

    1. The George Washington University Medical Center, Washington, USA

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Table of contents (43 chapters)

  1. Front Matter

    Pages i-x
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  2. Peptides

    1. Front Matter

      Pages 1-1
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    2. Distribution of Endothelin, a Putative Growth Promoting Peptide, Using Modern Microscopical Imaging Methods

      • Julia M. Polak, Giorgio Terenghi
      Pages 3-13

    3. Vasoactive Intestinal Peptide: From Molecular Genetics to Neurotropism

      • Illana Gozes, Douglas E. Brenneman
      Pages 15-20

    4. Design and Structure/Conformation-Activity Studies of a Prototypic Corticotropin-Releasing Factor (CRF) Antagonist: Multiple Alanine Substitutions of CRF12-41

      • Tomi K. Sawyer, Douglas J. Staples, Carol A. Bannow, John H. Kinner, Linda L. Maggiora, Dawna Evans et al.
      Pages 21-28

    5. Retinoic Acid Regulates preproVIP Expression in the Human Neuroblastoma Cell Line NB-1

      • Birgitte Georg, Birgitte S. Wulff, Jan Fahrenkrug
      Pages 29-35

    6. Structure-Dependent Inhibitory Effect of Galanin on Insulin, Gastric Acid and Pancreatic Amylase Secretion in Rat

      • Wojciech J. Rossowski, David H. Coy
      Pages 37-50

    7. Amphibian Opioids: Novel Dermorphin-Like Peptides

      • Lucia Negri
      Pages 51-60

    8. Proteases for Neuropeptide Precursor Processing in Bovine Adrenal Medullary Chromaffin Granules

      • Vivian Y. H. Hook, Anahit V. Azaryan, Timothy J. Krieger
      Pages 61-70

    9. Amylin and Neuromedin U - Two Novel Regulatory Peptides of the Gastroenteropancreatic System

      • S R Bloom
      Pages 71-79

  3. Growth Factors

    1. Front Matter

      Pages 81-81
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    2. Gene Transfer into the Central Nervous System: Neurotrophic Factors

      • David M. Frim, Julie K. Andersen, James M. Schumacher, M. Priscilla Short, Ole Isacson, Xandra Breakefield
      Pages 83-91

    3. The Structural and Biological Properties of Heparin-Binding Egf- Like Growth Factor (HB-EGF)

      • Shigeki Higashiyama, Michael Klagsbrun
      Pages 93-100

    4. Structural Organization of the Multiple Tgf- ßGenes

      • Sonia B. Jakowlew
      Pages 101-113

    5. Dexamethasone Modulates the Response of Rat Stromal Bone Marrow Derived Bone-Like Cells to bFGF and Igf-I

      • Naphtali Savion, Anat Beit-Or, Shlomo Kotev-Emeth, Sandu Pitaru
      Pages 115-126

    6. Behavioral, Hormonal and Neurochemical Alterations in Transgenic Mice Overexpressing Transforming Growth Factorα

      • Leena Hilakivi-Clarke, Richard Goldberg, Robert B. Dickson
      Pages 127-136

    7. Growth Factors and Brain Injury

      • David J. Berlove, Seth P. Finklestein
      Pages 137-146

    8. The Basic Fibroblast Growth Factor Isoforms: Endogenous and Exogenous Behavior

      • Natalina Quarto, Gérard Bouche, Béatrix Bugler, Catherine Chailleux, Hervé Prats, Anne-Catherine Prats et al.
      Pages 147-158

  4. Peptide Receptors

    1. Front Matter

      Pages 159-159
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    2. Structural Analysis of Ligand Binding Characteristics for the Bombesin/Gastrin-Releasing Peptide Receptor

      • David H. Coy, Robert T. Jensen
      Pages 161-170
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Keywords

About this book

The Twelfth Annual Washington Spring Symposium on Health Sciences attracted over 300 scientists from 20 countries. It was held at the Lisner Auditorium of the George Washington University in Washington, D.C. during June 1-5, 1992. The theme of the meeting was "Growth Factors, Peptides, and Receptors," and speakers emphasized both basic and clinical research in these areas. The seven plenary sessions emphasized Peptides, Growth Factors, Peptide Receptors, Growth Factor Receptors, Second Messengers, Proliferation, and Clinical Correlations. The chapters in this volume are derived from each of these scientific sessions plus the poster and special sessions. The Abraham White Distinguished Scientist Award was presented to Dr. Solomon H. Snyder for his numerous contributions to the field of neurochemistry. He presented the keynote address "Nitric Oxide: A Novel Neuronal Messenger." Dr. Snyder discussed the pathway of nitric oxide (NO) synthesis by the enzyme NO synthase. Released NO may be responsible for the neuronal toxicity associated with NMDA, an excitatory amino acid analogue. Dr. Snyder noted that NO may be the first of a new class of transmitters, with carbon monoxide being another candidate. The Distinguished Public Service Award was presented to Senator Fritz Hollings in of his leadership and outstanding achievements in the United States Senate recognition and for his legislative support for biomedical research and education. In the symposium banquet address, Senator Hollings stressed the need for continued support of research to combat serious diseases such as cancer.

Editors and Affiliations

  • The George Washington University Medical Center, Washington, USA

    Terry W. Moody

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