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  • © 2018

Zic family

Evolution, Development and Disease

Editors:

  • Is the first comprehensive review of the Zic family-related studies in biology and medicine
  • Presents the Zic genes for the nervous system appearance is utilized in the animal evolution
  • Provides the cutting edge information for common genetic disorders, stem cell and cancer cell biology

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1046)

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eBook USD 129.00
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  • Read on any device
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Softcover Book USD 169.99
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  • Dispatched in 3 to 5 business days
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Hardcover Book USD 169.99
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  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
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Table of contents (18 chapters)

  1. Front Matter

    Pages i-x
  2. Zic Family in Animal Evolution and Development

    1. Front Matter

      Pages 1-1
    2. Comparative Genomics of the Zic Family Genes

      • Jun Aruga, Minoru Hatayama
      Pages 3-26
    3. Cnidarian Zic Genes

      • Michael J. Layden
      Pages 27-39
    4. Odd-Paired: The Drosophila Zic Gene

      • Deborah A. Hursh, Brian G. Stultz
      Pages 41-58
    5. Lophotrochozoan Zic Genes

      • Jun Aruga
      Pages 69-86
    6. Ascidian Zic Genes

      • Yutaka Satou, Kaoru S. Imai
      Pages 87-106
    7. Amphibian Zic Genes

      • Christa Merzdorf, Jennifer Forecki
      Pages 107-140
    8. Zic Genes in Teleosts: Their Roles in Dorsoventral Patterning in the Somite

      • Kota Abe, Toru Kawanishi, Hiroyuki Takeda
      Pages 141-156
    9. Zebrafish Zic Genes Mediate Developmental Signaling

      • Cecilia Lanny Winata, Vladimir Korzh
      Pages 157-177
    10. Overview of Rodent Zic Genes

      • Koula E. M. Diamand, Kristen S. Barratt, Ruth M. Arkell
      Pages 179-207
    11. Rodent Zic Genes in Neural Network Wiring

      • Eloísa Herrera
      Pages 209-230
  3. Zic Family in Medicine

    1. Front Matter

      Pages 231-231
    2. ZIC2 in Holoprosencephaly

      • Kristen S. Barratt, Ruth M. Arkell
      Pages 269-299
    3. ZIC3 in Heterotaxy

      • Helen M. Bellchambers, Stephanie M. Ware
      Pages 301-327
    4. Deregulation of ZIC Family Members in Oncogenesis

      • Rob Houtmeyers, Jabob Souopgui, Sabine Tejpar
      Pages 329-338

About this book

This book provides a comprehensive overview of ZIC-family research. Part1 summarizes the ZIC family in animal evolution and development and presents an overall picture of the ZIC family gene structure in eumetazoan animals, providing an evolutionary hypothesis and reviewing the studies on the role of ZIC family proteins in developmental processes for each animal model. Part 2 shows that the ZIC family are the causative genes for developmental disorders, and discusses the role of the ZIC family in stem cell biology. It also presents studies on the ZIC family in the medical biology field. This interdisciplinary book is a valuable resource not only for those people directly involved in ZIC-family-related research, but also researchers in diverse research fields who are interested in the latest advances in biology and medicine. 

 

Editors and Affiliations

  • Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan

    Jun Aruga

About the editor

Jun Aruga is a professor of pharmacology at Nagasaki University Institute of Biomedical Sciences, and a former head of the Laboratory for Behavioral and Developmental Disorder at RIKEN Brain Science Institute. He has been researching the biological significance of ZIC family genes since their discovery in 1991.

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access