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Notch Signaling

Immunity and Cancer

Editors: Yasutomo, Koji (Ed.)

  • Covers all areas of Notch functions in immune cells and tumorigenesis
  • Provides coverage of controversial issues, further facilitating research in this field
  • Includes detailed descriptions of the relationship of Notch signaling to human diseases
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Buy this book

eBook $109.00
price for USA (gross)
  • ISBN 978-981-10-4971-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.00
price for USA
  • ISBN 978-981-10-4970-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book covers the broad area related to Notch-mediated regulation of the immune system and tumorigenesis. Notch signaling was originally identified as a crucial pathway to regulate cell fate choice. Subsequent studies, however, have revealed that Notch regulates many steps of immune cell differentiation or development as well as tumorigenesis of cells. Although there are still many controversial issues regarding the functions or regulatory mechanism of Notch, it is important to summarize all data together in one volume to help facilitate this research area. Also, the studies regarding the functions of Notch in immune cells and tumor cells have motivated researchers and pharmaceutical companies to develop drugs for treating immune-mediated diseases and tumors. Therefore, this book covering the broad area of Notch in immunology and tumorigenesis will be attractive to many researchers including faculty members and postdoctoral fellows in academia and researchers in the pharmaceutical industry.

About the authors

Koji Yasutomo, M.D., Ph.D.
Department of Immunology and Parasitology, Graduate School of Medicine
Tokushima University
Tokushima, Japan

Table of contents (6 chapters)

  • Notch Ligands for Lymphocyte Development

    Hozumi, Katsuto

    Pages 3-20

  • Notch Controls the Differentiation and Function of Cytotoxic CD8 T Cells

    Maekawa, Yoichi (et al.)

    Pages 21-33

  • Notch and Myeloid Cells

    Ishifune, Chieko (et al.)

    Pages 35-55

  • Taking CD4 T Cells Up a Notch

    Helbig, Christina (et al.)

    Pages 57-75

  • NOTCH in Malignant Lymphoma

    Chiba, Shigeru

    Pages 79-92

Buy this book

eBook $109.00
price for USA (gross)
  • ISBN 978-981-10-4971-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.00
price for USA
  • ISBN 978-981-10-4970-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Notch Signaling
Book Subtitle
Immunity and Cancer
Editors
  • Koji Yasutomo
Copyright
2017
Publisher
Springer Singapore
Copyright Holder
Springer Nature Singapore Pte Ltd.
eBook ISBN
978-981-10-4971-2
DOI
10.1007/978-981-10-4971-2
Hardcover ISBN
978-981-10-4970-5
Edition Number
1
Number of Pages
VII, 104
Number of Illustrations and Tables
3 b/w illustrations, 12 illustrations in colour
Topics