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  • © 2019

Lymph Node Metastasis in Gastrointestinal Cancer

Editors:

  • Broadens understanding of lymph node micrometastasis in gastrointestinal cancers

  • Presents the latest status of sentinel node navigation surgery for gastrointestinal cancers

  • Elucidates the whole picture of basic and clinical approaches for lymph node micrometastasis and sentinel node navigation surgery

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-viii
  2. Physiology of the Gastrointestinal Lymphatics

    • Toshio Ohhashi, Yoshiko Kawai
    Pages 1-16
  3. Anatomy of Lymphatics

    • Tatsuo Sato
    Pages 17-67
  4. Molecular Mechanisms of Lymph Node Metastasis

    • Naohide Oue, Yasuhiko Kitadai, Wataru Yasui
    Pages 69-92
  5. Basic Science of the Lymphatic System

    1. Front Matter

      Pages 93-93
    2. Immunology of a Lymph Node

      • Ryota Hokari, Soichiro Miura
      Pages 95-110
    3. Lymphoid Tissues Associated with Gastrointestinal (GI) Mucosa

      • Takahiro Nagatake, Jun Kunisawa, Hiroshi Kiyono
      Pages 111-126
    4. Nonclinical Imaging Studies for the Diagnosis of Lymph Node Metastases

      • Kazunobu Ohnuki, Hirofumi Fujii
      Pages 127-157
    5. In Vivo Imaging of Lymphatic Vessels and Lymph Nodes

      • Takeshi Imamura, Takashi Saitou, Sota Takanezawa, Ryosuke Kawakami
      Pages 159-176
  6. Lymph Node Micrometastasis

    1. Front Matter

      Pages 177-177
    2. Basic Aspect: Methodology

      • Shuhei Ito, Takaaki Masuda, Yosuke Kuroda, Hidetoshi Eguchi, Koshi Mimori
      Pages 179-193
    3. Clinical Aspect: Esophageal Cancer

      • Itaru Omoto, Yasuto Uchikado, Ken Sasaki, Takaaki Arigami, Shoji Natsugoe
      Pages 195-207
    4. Clinical Aspect: Gastric Cancer

      • Takaaki Arigami, Yoshikazu Uenosono, Shigehiro Yanagita, Sumiya Ishigami, Shoji Natsugoe
      Pages 209-223
    5. Clinical Aspects: Colorectal Cancer

      • Hirofumi Yamamoto, Masaki Mori
      Pages 225-236
    6. Esophageal Cancer

      • Yoshiaki Kajiyama, Natsumi Tomita, Takashi Hashimoto
      Pages 249-263
  7. Lymph Node Metastasis: Clinical Significance

    1. Front Matter

      Pages 265-265
    2. Gastric Cancer

      • Koshi Kumagai, Takeshi Sano
      Pages 267-282
    3. Colorectal Cancer

      • Kazushige Kawai, Kensuke Otani, Manabu Kaneko, Koji Murono, Kazuhito Sasaki, Toshiaki Watanabe
      Pages 283-302
  8. Sentinel Node Navigation Surgery

    1. Front Matter

      Pages 303-303

About this book

This book provides the most comprehensive and up-to-date knowledge of lymph node micrometastasis (LMM) and sentinel node navigation surgery (SNNS) in gastrointestinal cancers.

Lymph node metastasis is a critically important prognostic factor in gastrointestinal tract cancers such as tumors of the esophagus, stomach, and colorectum. An understanding of the basic aspects of lymphatics and lymph nodes, including anatomy, histology, physiology, immunology, and molecular biology, is fundamental for physicians who are involved in cancer treatment. Furthermore, owing to the development of molecular and biological methodology, the precise recognition of LMM and its clinical significance have been clarified recently.

At the same time, SNNS has actually been anticipated in treatment of breast tumors, and it is now being introduced in gastrointestinal tract cancer. For the application of SNNS, the detection of lymph node metastasis including LMM is extremely significant, because the presence of LMM determines the direction for surgery and chemo and/or radiation therapy.

With these considerations in mind, the expert contributors to this book review basic and clinical approaches for LMM and SNNS including methodology for gastrointestinal cancers. Thus this volume benefits not only surgeons who treat gastrointestinal cancers but also clinical oncologists and medical scientists such as physiologists and pathologists.

Editors and Affiliations

  • Department of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima, Japan

    Shoji Natsugoe

About the editor

Dr. Shoji Natsugoe

Professor

Department of Digestive Surgery, Breast and Thyroid Surgery,

Kagoshima University Graduate School of Medical and Dental Sciences,

Kagoshima, Japan

Bibliographic Information

  • Book Title: Lymph Node Metastasis in Gastrointestinal Cancer

  • Editors: Shoji Natsugoe

  • DOI: https://doi.org/10.1007/978-981-10-4699-5

  • Publisher: Springer Singapore

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2019

  • Hardcover ISBN: 978-981-10-4698-8Published: 05 February 2019

  • eBook ISBN: 978-981-10-4699-5Published: 23 January 2019

  • Edition Number: 1

  • Number of Pages: VIII, 358

  • Number of Illustrations: 25 b/w illustrations, 116 illustrations in colour

  • Topics: Oncology, Surgery, Pathology

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access