Heat Shock Proteins

Prokaryotic Chaperonins

Multiple Copies and Multitude Functions

Editors: Kumar, C. M. Santosh, Mande, Shekhar C. (Eds.)

  • This book discusses recent advances in understanding of the chaperonins and particularly multiple chaperonins
  • The book covers evolution and possible modes of distribution of the multiple chaperonins, which is a novel topic on chaperonins
  • Numerous halftones and line figures help the reader to understand and learn quickly
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eBook $129.00
price for USA (gross)
  • ISBN 978-981-10-4651-3
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.00
price for USA
  • ISBN 978-981-10-4650-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book focuses on a topical and timely aspect of prokaryotic biology - the biology of prokaryotic multiple chaperonins. Chaperonins are a class of molecular chaperones, the proteins that assist folding of other proteins in the cell. The book begins with an introductory chapter on the structural and functional aspects of chaperonins, followed by an outline on different mechanisms of their regulation. Subsequently, the book provides a comprehensive overview on how the multiple-chaperonins have embraced biological requirements in different classes of microbes, discussing their functional diversity, evolutionary paths and the latest advances in the field.

It brings together leading experts from across the globe in offering a detailed account of the structural, biochemical, functional and phylogenetic characteristics of microbial chaperonins for students, researchers and teachers working in the area of microbiology/ biophysics/ parasitology – more specifically, in protein folding pathways. 

About the authors

C. M. Santosh Kumar started his research career as a molecular geneticist, exploring the functions of molecular chaperones in health and disease. His research aims at understanding the functions of the bacterial chaperonins, especially those of the multiple chaperonins. He has demonstrated that activity of a mycobacterial chaperonin is regulated by a phosphorylation switch that facilitates oligomerization. His current interests include unravelling the role of mycobacterial chaperonins in the establishment and progression of tubercular disease.

 

Shekhar C. Mande is a structural biologist interested in understanding the molecular attributes of mycobacterial stress proteins. He started his career as a structural biologist in understanding the structural features of peanut lectin. Further, he became interested in the structure-function relations of mycobacterial stress proteins, such as the redox proteins and heat-shock proteins. He led the way towards the understanding of structural features of the mycobacterial chaperonin proteins. His work demonstrated that mycobacterial chaperonins exhibit non-canonical attributes that are evolved to assist the pathogen in its disease establishment and progression. Concurrently, he began to explore the system wide functional interactions among the mycobacterial proteins. These investigations have led to the identification of several novel interactions that are currently being examined.

Table of contents (1 chapters)

  • Multiple Chaperonins and Their Potential Roles in Rhizobia

    Lund, Peter A.

    Pages 81-91

Buy this book

eBook $129.00
price for USA (gross)
  • ISBN 978-981-10-4651-3
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.00
price for USA
  • ISBN 978-981-10-4650-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Prokaryotic Chaperonins
Book Subtitle
Multiple Copies and Multitude Functions
Editors
  • C. M. Santosh Kumar
  • Shekhar C. Mande
Series Title
Heat Shock Proteins
Series Volume
11
Copyright
2017
Publisher
Springer Singapore
Copyright Holder
Springer Nature Singapore Pte Ltd.
eBook ISBN
978-981-10-4651-3
DOI
10.1007/978-981-10-4651-3
Hardcover ISBN
978-981-10-4650-6
Series ISSN
1877-1246
Edition Number
1
Number of Pages
IX, 170
Number of Illustrations and Tables
8 b/w illustrations, 38 illustrations in colour
Topics