Subcellular Biochemistry

Urea Transporters

Editors: Yang, Baoxue, Sands, Jeff M. (Eds.)

  • Covers research advances in the study of urea transporter over the past 20 years
  • Provides a systematic and comprehensive insight into urea transporters
  • Introduces clinical and pharmaceutical aspects of urea and urea transporters, linking the bench work to the bedside
  • Written by experts in this field
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eBook $159.00
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  • ISBN 978-94-017-9343-8
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  • Immediate eBook download after purchase
Hardcover $209.00
price for USA
  • ISBN 978-94-017-9342-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: August 31, 2016
  • ISBN 978-94-024-0227-8
  • Free shipping for individuals worldwide
About this book

The mechanisms and physiological functions of urea transporters across biological membranes are subjects of long-standing interests. Although urea represents roughly 40% of all urinary solutes in normal human urine, the handling of urea in the tissues has been largely neglected in the past and few clinical or experimental studies now report data on urea. Most recent physiological text books include chapters on water and electrolyte physiology but no chapter on urea. Our aim in writing this book is to stimulate further research in new directions by providing novel and provocative insights into the further mechanisms and physiological significance of urea metabolism and transport in mammals. This book offers a state-of-the-art report on recent discoveries concerning urea transport and where the field is going. It mainly focuses on advances made over the past 20 years on the biophysics, genetics, protein structure, molecular biology, physiology, pathophysiology and pharmacology of urea transport in mammalian cell membranes. It will help graduate students and researchers to get an overall picture of mammalian urea transporters and may also yield benefits for pharmaceutical companies with regard to drug discovery based on the urea transporter. Baoxue Yang is a professor and vice chairman of the Department of Pharmacology, Peking University. He is also an adjunct professor of Jilin University and a visiting professor of Northeast Normal University. Prof. Yang has been researching urea transporters for nearly 20 years and has published more than 70 original research articles in this field.

About the authors

Baoxue Yang is a professor and vice chairman of Department of Pharmacology, Peking University. He is also an adjunct professor of Jilin University and a visiting professor of Northeast Normal University. Prof. Yang has been studying on urea transporter for nearly 20 years and published more than 70 original research articles in this field.

Jeff M. Sands is the Juha P. Kokko Professor of Medicine and Physiology, Director of the Renal Division, and Executive Vice-Chair of the Department of Medicine at Emory Universtiy School of Medicine. Dr. Sands' research focuses on urea transport proteins and the urine concentrating mechanisms.

Table of contents (14 chapters)

  • Overview and Historical Perspective

    Yang, Baoxue (et al.)

    Pages 1-5

  • Urea

    Wang, Hongkai (et al.)

    Pages 7-29

  • Mathematical Modeling of Urea Transport in the Kidney

    Layton, Anita T.

    Pages 31-43

  • Genes and Proteins of Urea Transporters

    Sands, Jeff M. (et al.)

    Pages 45-63

  • Structure of Urea Transporters

    Levin, Elena J. (et al.)

    Pages 65-78

Buy this book

eBook $159.00
price for USA (gross)
  • ISBN 978-94-017-9343-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $209.00
price for USA
  • ISBN 978-94-017-9342-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: August 31, 2016
  • ISBN 978-94-024-0227-8
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Urea Transporters
Editors
  • Baoxue Yang
  • Jeff M. Sands
Series Title
Subcellular Biochemistry
Series Volume
73
Copyright
2014
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-017-9343-8
DOI
10.1007/978-94-017-9343-8
Hardcover ISBN
978-94-017-9342-1
Softcover ISBN
978-94-024-0227-8
Series ISSN
0306-0225
Edition Number
1
Number of Pages
X, 265
Number of Illustrations and Tables
16 b/w illustrations, 49 illustrations in colour
Topics