MFG-E8 and Inflammation

Editors: Wang, Ping (Ed.)

  • Simple and easy illustration of the complex network of innate immune system in human diseases
  • A number of novel mechanistic aspects highlighting MFG-E8's therapeutic potential
  • Includes several animal models relevant to critical care medicine and inflammatory diseases
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eBook $149.00
price for USA (gross)
  • ISBN 978-94-017-8765-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-94-017-8764-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: November 4, 2016
  • ISBN 978-94-024-0332-9
  • Free shipping for individuals worldwide
About this book

After the discovery of milk fat globule-epidermal growth factor-factor 8 (MFG-E8) about two decades ago, a new era of delineating its potential beneficial role in several inflammatory diseases has begun to spout from the bench to translational research. In MFG-E8 and Inflammation, the editor and contributors have gathered a remarkable collection covering novel discoveries on the rapidly growing field of MFG-E8 and Inflammation which includes not only the findings from their individual lobotomies, but also from a host of pioneering researchers of this field. MFG-E8 and Inflammation starts by describing the origin, structure, expression, functions and regulation of MFG-E8, and then continues thoughtfully exploring its potentiality as a marker for apoptotic, stressed and activated cells. The topics cover the cellular and physiological function of MFG-E8, especially its role in efficient phagocytosis of apoptotic cells, intestinal barrier function, blood cell homeostasis and coagulation, and in the maintenance of the intact vascular system. The role of MFG-E8 in macrophages, neutrophils, lymphocytes, dendritic cells, platelets, as well as non-hematopoietic cells is adequately described in the book. The chapters also contain several lucid discussions on the recent discoveries of the roles of MFG-E8 in the autoimmune diseases, sepsis, tissue ischemia-reperfusion, hemorrhage, inflammatory bowel diseases, acute lung injury, asthma, lung fibrosis, stroke, prion diseases and Alzheimer’s diseases with the potential focus on elucidating novel mechanistic pathways. MFG-E8 and Inflammation is an indispensable resource for scientists and clinical researchers working on fundamental or applied aspects of MFG-E8 pathobiology. This book explores, dissects and reviews several noteworthy findings and striking future perspectives which not only rewrite the disease pathophysiology, but also update our understanding towards attaining novel therapeutic potentials against various inflammatory diseases.

About the authors

Ping Wang, MD, is the Vice Chairman for Research at the Department of Surgery, and Professor of Surgery and Molecular Medicine at Hofstra North Shore-LIJ School of Medicine. He is also the Head of the Center for Translational Research at the Feinstein Institute for Medical Research. Previously, Dr. Wang has held positions of Associate Professor of Surgery at Brown University School of Medicine and Professor of Surgery, Pathology, Physiology and Biophysics at University of Alabama at Birmingham (UAB), as well as Professor of Surgery at Albert Einstein College of Medicine. His laboratory has been continually funded by the NIH since 1995. Dr. Wang has published over 300 peer-reviewed articles in the field of inflammation research.

Table of contents (10 chapters)

  • MFG-E8: Origin, Structure, Expression, Functions and Regulation

    Oshima, Kenzi (et al.)

    Pages 1-31

  • MFG-E8 as a Marker for Apoptotic, Stressed and Activated Cells

    Blans, Kristine (et al.)

    Pages 33-54

  • Role of MFG-E8 in Protection of Intestinal Epithelial Barrier Function and Attenuation of Intestinal Inflammation

    Akhtar, Suhail (et al.)

    Pages 55-63

  • MFG-E8 in the Blood Cell Homeostasis and Coagulation

    Dasgupta, Swapan Kumar (et al.)

    Pages 65-84

  • MFG-E8 in the Vascular System

    Li, Xuan (et al.)

    Pages 85-95

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-94-017-8765-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-94-017-8764-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: November 4, 2016
  • ISBN 978-94-024-0332-9
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
MFG-E8 and Inflammation
Editors
  • Ping Wang
Copyright
2014
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-017-8765-9
DOI
10.1007/978-94-017-8765-9
Hardcover ISBN
978-94-017-8764-2
Softcover ISBN
978-94-024-0332-9
Edition Number
1
Number of Pages
XV, 198
Number of Illustrations and Tables
9 b/w illustrations, 21 illustrations in colour
Topics