Eco-immunology

1. Front Matter

   Pages i-xii

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2. From Immunology to Eco-Immunology: More than a New Name

   • Mark E. Viney, Eleanor M. Riley

   Pages 1-19

3. System Biology Models and Conceptualizations Applied to Eco-Immunology

   • Dominik Wodarz

   Pages 21-47

4. Reproductive and Immune System Interactions in the Context of Life History and Sexual Selection Theory

   • Kenneth M. Fedorka

   Pages 49-72

5. Host-Parasite Interactions

   • Jeb P. Owen, Dana M. Hawley

   Pages 73-92

6. Immune-Neuroendocrine Integration and Its Evolution

   • D. Malagoli, E. Ottaviani

   Pages 93-104

7. Thymic Maturation and Programmed Cell Death

   • Daniela Quaglino, Alice Accorsi, Federica Boraldi, Enzo Ottaviani

   Pages 105-124

8. The New Antigenic Ecospace of the Globalized World and its Impact on the Immune System: The Battleground of Trade-off and Antagonistic Pleiotropy

   • Miriam Capri, Stefano Salvioli, Daniela Monti, Laura Bucci, Paolo Garagnani, Enzo Ottaviani et al.

   Pages 125-144

9. Population Immunology: Germs, Aging and Inflammation

   • Ana Maria C. Faria, Claudio Franceschi

   Pages 145-161

10. Mouse Models as Paradigms of Human Diseases

    • Lloyd A. Demetrius, Davide Malagoli

    Pages 163-177

11. Back Matter

    Pages 179-179

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This book represents a cutting-edge contribution giving an all-around perspective of eco-immunology today. Beside questions of the utmost importance for the whole community of immunologists, e.g, the intrinsic limits of immunological experiments performed at the bench on a limited number of selected models, the book covers several other facets of the eco-immunological approach, including host-parasite interactions, human aging and population immunology. Throughout the book the importance of population dynamics and evolutionary diversification of immune systems is frequently recalled, and makes the reader aware of the basic similarities and differences existing between humans and the models adopted for studying human immune system. The evidenced differences have been recently challenging the reliability of several established animal models and in the book it is discussed for the first time in analytical terms whether mice are reliable models of human inflammatory disorders.

• Comparative Biology
• Eco-immunology
• Evolution
• Immunology
• Laboratory Models
• systems biology

• University of Modena and Reggio Emilia, Modena, Italy

  Davide Malagoli, Enzo Ottaviani

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