Topics in Current Chemistry

Aminoacyl-tRNA Synthetases in Biology and Medicine

Editors: Kim, Sunghoon (Ed.)

  • Will attract broad readership from basic life science to biotechnology and medical community
  • Describes how aminoacyl-tRNA synthetases give insight into the emergence and evolution of life
  • Shows how the function of a gene can be diversified at protein level
  • Describes how a central metabolism such as protein synthesis is coordinated with other cellular processes
  • Covers ARS-related pathologies and novel activities, which provide new understanding of human diseases and therapeutic opportunities
  • Written by leading experts in the field
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Buy this book

eBook $269.00
price for USA (gross)
  • ISBN 978-94-017-8701-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $349.00
price for USA
  • ISBN 978-94-017-8700-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $349.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: October 21, 2016
  • ISBN 978-94-024-0633-7
  • Free shipping for individuals worldwide
About this book

This book will focus on new molecular interactions and novel activities and the associated diseases that have been recently discovered from the studies of eukaryotic and mammalian aminoacyl-tRNA synthetases. In addition, the potential applications of ARS researches in biotechnology and medicine will be addressed.

About the authors

1983–1986 Researcher, Genetic Eng. Center, KAIST, Korea
1991–1994 Post-doc, MIT, USA
1993–1994 Senior Scientist, Cubist Pharmaceuticals, USA
1994-2001 Associate Professor, Sung Kyun Kwan University, Korea
2001-present Professor, College of Pharmacy, Graduate Program in Bioinformatics , Genetic Engineering, Cancer Biology, Seoul National Univ.
1998-present Director, Center for Medicinal Protein Network and Systems Biology, Seoul National University
2008- Director, Information Center of Bio-pharmacological Network
2008- Director, Integrated Bioscience and Biotechnology Institute

Table of contents (11 chapters)

  • Synthetic and Editing Mechanisms of Aminoacyl-tRNA Synthetases

    Perona, John J. (et al.)

    Pages 1-41

  • Emergence and Evolution

    Bullwinkle, Tammy J. (et al.)

    Pages 43-87

  • Architecture and Metamorphosis

    Guo, Min (et al.)

    Pages 89-118

  • Protein–Protein Interactions and Multi-component Complexes of Aminoacyl-tRNA Synthetases

    Kim, Jong Hyun (et al.)

    Pages 119-144

  • Extracellular Activities of Aminoacyl-tRNA Synthetases: New Mediators for Cell–Cell Communication

    Son, Sung Hwa (et al.)

    Pages 145-166

Buy this book

eBook $269.00
price for USA (gross)
  • ISBN 978-94-017-8701-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $349.00
price for USA
  • ISBN 978-94-017-8700-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $349.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: October 21, 2016
  • ISBN 978-94-024-0633-7
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Aminoacyl-tRNA Synthetases in Biology and Medicine
Editors
  • Sunghoon Kim
Series Title
Topics in Current Chemistry
Series Volume
344
Copyright
2014
Publisher
Springer Netherlands
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-94-017-8701-7
DOI
10.1007/978-94-017-8701-7
Hardcover ISBN
978-94-017-8700-0
Softcover ISBN
978-94-024-0633-7
Series ISSN
0340-1022
Edition Number
1
Number of Pages
X, 350
Topics