Developments in Nuclear Medicine

PET Studies on Amino Acid Metabolism and Protein Synthesis

Proceedings of a Workshop held in Lyon, France within the framework of the European Community Medical and Public Health Research

Editors: Mazoyer, B.M., Heiss, WD, Comar, D. (Eds.)

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About this book

Parameters such as membrane transport, metabolism and protein incorporation govern the fate of amino acids in living tissue. Is it possible to use positron tomography to measure some of them, and what is their meaning in normal and pathological situations? These questions have been addressed for a long time and no satisfactory answer has yet been given.
This book, which derives from an EEC workshop organized in the frame of the Concerted Action on `PET Investigation of Cellular Regeneration and Degeneration', held in Lyon in February 1992, gives the present state of knowledge in this field based on the most recent studies. Contributions from 24 leading European and American scientists are presented and discussed in the following four parts:

  • biochemistry and animal studies;
  • amino acids labelling with positron emittors, quality control and metabolites measurement;
  • kinetic modelling of amino acids transport, metabolism, and protein incorporation;
  • clinical use of amino acids.
This book will aid and interest biochemists, radiochemists, pharmacologists, neurologists, oncologists and medical imaging scientists.

Table of contents (22 chapters)

  • Cerebral Protein Turnover: Aspects and Problems

    Lajtha, A. (et al.)

    Pages 1-17

  • Determination of Regional Rates of Cerebral Protein Synthesis in Vivo with L-[1-14C]Leucine as the Tracer Amino Acid

    Smith, C. Beebe

    Pages 19-39

  • Methionine Metabolism in Rat Brain

    Bobillier, P. (et al.)

    Pages 41-52

  • Protein Synthesis Studies in Rats with Methionine

    Planas, A. M. (et al.)

    Pages 53-68

  • Carbon-11 Amino Acids, Labeling and Metabolites

    Vaalburg, Willem (et al.)

    Pages 75-80

Buy this book

eBook $99.00
price for USA (gross)
  • ISBN 978-94-011-1620-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $129.00
price for USA
  • ISBN 978-94-010-4706-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
PET Studies on Amino Acid Metabolism and Protein Synthesis
Book Subtitle
Proceedings of a Workshop held in Lyon, France within the framework of the European Community Medical and Public Health Research
Editors
  • B.M. Mazoyer
  • WD Heiss
  • D. Comar
Series Title
Developments in Nuclear Medicine
Series Volume
23
Copyright
1993
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-011-1620-6
DOI
10.1007/978-94-011-1620-6
Softcover ISBN
978-94-010-4706-7
Edition Number
1
Number of Pages
XIV, 270
Topics