Heat Shock Proteins of Malaria

Editors: Shonhai, Addmore, Blatch, Gregory Lloyd (Eds.)

  • This is a novel area of malaria research that is very topical
  • All of the chapters are written by leaders or experts in the field
  • The chapters on drug discovery will appeal to the biotechnology industry
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eBook $149.00
price for USA (gross)
  • ISBN 978-94-007-7438-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-94-007-7437-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-94-024-0259-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book describes the role of heat shock proteins in the life cycle of malaria parasites. The work includes a general introduction on the structural and functional features of heat shock proteins. The main focus is on the role of heat shock protein families from Plasmodium falciparum, their role in protein folding and in the development of malaria pathology. The functions of individual families of heat shock proteins from plasmodium species and their cooperation in functional networks is described. Subcellular and extracellular organelles such as the apicoplast and the Maurer’s Clefts which are associated with plasmodium species, are discussed in detail. The role of heat shock proteins in the development and function of these organelles structures are highlighted. Although conceding that heat shock proteins may not be ideal antimalarial drug targets, prospects of targeting heat shock proteins in antimalarial drug discovery either directly and/or in combination therapies are explored.

Table of contents (11 chapters)

  • The Importance of Molecular Chaperones in Survival and Pathogenesis of the Malaria Parasite Plasmodium falciparum

    Przyborski, Jude

    Pages 1-3

  • General Structural and Functional Features of Molecular Chaperones

    Edkins, Adrienne L. (et al.)

    Pages 5-45

  • The Role of Hsp70s in the Development and Pathogenicity of Plasmodium Species

    Shonhai, Addmore

    Pages 47-69

  • Role of the Hsp40 Family of Proteins in the Survival and Pathogenesis of the Malaria Parasite

    Pesce, Eva-Rachele (et al.)

    Pages 71-85

  • Role of Hsp90 in Plasmodium falciparum Malaria

    Shahinas, Dea (et al.)

    Pages 87-97

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-94-007-7438-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-94-007-7437-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-94-024-0259-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Heat Shock Proteins of Malaria
Editors
  • Addmore Shonhai
  • Gregory Lloyd Blatch
Copyright
2014
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-007-7438-4
DOI
10.1007/978-94-007-7438-4
Hardcover ISBN
978-94-007-7437-7
Softcover ISBN
978-94-024-0259-9
Edition Number
1
Number of Pages
VIII, 223
Number of Illustrations and Tables
2 b/w illustrations, 33 illustrations in colour
Topics