Stem Cells and Cancer Stem Cells

Stem Cells and Cancer Stem Cells, Volume 11

Therapeutic Applications in Disease and injury

Editors: Hayat, M.A. (Ed.)

  • Covers all varieties of stem cells: pluripotent, multipotent and unipotent cells Includes nine chapters devoted to cancer stem cells
  • Offers comprehensive review of the therapeutic application of stem cells for regeneration of bones, as biomarkers and in the treatment of the injured spinal cord
  • Expert contributors include oncologists, neurosurgeons, physicians, research scientists and pathologists
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eBook $159.00
price for USA (gross)
  • ISBN 978-94-007-7329-5
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $209.00
price for USA
  • ISBN 978-94-007-7328-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
price for USA
  • ISBN 978-94-024-0750-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Volume 11 in this series discusses therapeutic applications of stem cells in disease and tissue injury. Coverage includes pluripotent stem cells, which can give rise to the endodermal, ectodermal, and mesodermal lineages; multipotent stem cells, which can generate all cells in a particular lineage and unipotent stem cells, which can give rise to only one cell type. This volume also examines cancer stem cells, tumor-initiating cells which possesses the capacity of self-renewal and can give rise to the heterogeneous lineages of cancer cells that comprise the tumor. Coverage extends to molecular mechanisms underlying the derivation and expansion of human embryonic stem cells, the role of specific proteins in the maintenance and inhibition of extraembryonic differentiation of these cells and the role of signaling responsible for the self-renewal of mouse embryonic stem cells. Nine chapters discuss the clinical importance of cancer stem cells, encompassing glioma, leukemia, ovarian cancer, pediatric sarcomas and head and neck squamous cell carcinoma. The role of cancer stem cells is also elucidated in epithelial-to-mesenchymal transition in spreading head and neck squamous cell carcinoma. The book goes on to survey therapeutic application of stem cells of hematopoietic and non-hematopoietic origin for regeneration of bones, including in osteoporotic bone disease; to illuminate the application of hematopoietic stem cells in bone regeneration and to discuss their use as a biomarker to facilitate determination of a treatment. The contributors review cells as biomarkers for pediatric solid tumors, and weigh the advantages and limitations of hematopoietic stem cell transplantation. Also included are details of neural stem cell engraftment in the injured spinal cord; the regenerative potential of neural stem/progenitor cells of newborns and cancer gene therapy potential using neural stem cells. Like the preceding volumes in the series, this book is distinguished for its comprehensive approach, its distinguished roster of 58 contributors representing 10 different countries and its thorough review of leading-edge technology and methods.

Table of contents (22 chapters)

  • Maintenance of Human Embryonic Stem Cell Identity and Inhibition of Extraembryonic Differentiation: Role of CNOT1, CNOT2 and CNOT3

    Dumitru, Raluca (et al.)

    Pages 3-14

  • Investigating the Role of the Embryonic Stem Cell Self-Renewal Gene NANOG in Neoplastic Processes

    Jeter, Collene R.

    Pages 15-27

  • Derivation and Expansion of Human Embryonic Stem Cells Under Xeno-Free, Defined Conditions

    Meng, Guoliang (et al.)

    Pages 29-39

  • Self-Renewal of Naïve State Mouse Embryonic Stem Cells: Role of LacdiNAc in LIF/STAT3 Signaling

    Nishihara, Shoko

    Pages 41-49

  • Cancer Gene Therapy Potential of Neural Stem Cells Derived from Human Embryonic Stem Cells and Induced Pluripotent Stem Cells

    Yang, Jing (et al.)

    Pages 51-63

Buy this book

eBook $159.00
price for USA (gross)
  • ISBN 978-94-007-7329-5
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $209.00
price for USA
  • ISBN 978-94-007-7328-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
price for USA
  • ISBN 978-94-024-0750-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Stem Cells and Cancer Stem Cells, Volume 11
Book Subtitle
Therapeutic Applications in Disease and injury
Editors
  • M.A. Hayat
Series Title
Stem Cells and Cancer Stem Cells
Series Volume
11
Copyright
2014
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-007-7329-5
DOI
10.1007/978-94-007-7329-5
Hardcover ISBN
978-94-007-7328-8
Softcover ISBN
978-94-024-0750-1
Series ISSN
2215-0994
Edition Number
1
Number of Pages
XXXVIII, 280
Number of Illustrations and Tables
8 b/w illustrations, 18 illustrations in colour
Topics