Systems Biology

Integrative Biology and Simulation Tools

Editors: Prokop, Ales, Csukas, Bela (Eds.)

  • This multi-authored volume presents a unique update in the field of pharmaceutical drugs
  • The book presents a unique coverage of computational problems and tools related to this field
  • The selected authors are all experts in their field
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eBook $159.00
price for USA (gross)
  • ISBN 978-94-007-6803-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $209.00
price for USA
  • ISBN 978-94-007-6802-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
price for USA
  • ISBN 978-94-007-9454-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Growth in the pharmaceutical market has slowed down – almost to a standstill. One reason is that governments and other payers are cutting costs in a faltering world economy. But a more fundamental problem is the failure of major companies to discover, develop and market new drugs. Major drugs losing patent protection or being withdrawn from the market are simply not being replaced by new therapies – the pharmaceutical market model is no longer functioning effectively and most pharmaceutical companies are failing to produce the innovation needed for success. This multi-authored new book looks at a vital strategy which can bring innovation to a market in need of new ideas and new products: Systems Biology (SB). Modeling is a significant task of systems biology. SB aims to develop and use efficient algorithms, data structures, visualization and communication tools to orchestrate the integration of large quantities of biological data with the goal of computer modeling. It involves the use of computer simulations of biological systems, such as the networks of metabolites comprise signal transduction pathways and gene regulatory networks to both analyze and visualize the complex connections of these cellular processes. SB involves a series of operational protocols used for performing research, namely a cycle composed of theoretical, analytic or computational modeling to propose specific testable hypotheses about a biological system, experimental validation, and then using the newly acquired quantitative description of cells or cell processes to refine the computational model or theory.

Reviews

From the reviews:

“This volume is the first of three planned books exploring the various tools used by the scientific community to deal with complexity in subjects such as big data, nonlinearity, and hidden interactions in systems biology. … welcomed by readers … who are directly or indirectly involved in the dynamic field of systems biology. The book offers insightful connections, knowledge that is often overlooked, and well-thought-out reasoning.” (Adrian Pasculescu, Computing Reviews, January, 2014)


Table of contents (19 chapters)

  • Functional Genomics, Proteomics, Metabolomics and Bioinformatics for Systems Biology

    Ballereau, Stéphane (et al.)

    Pages 3-41

  • Comparing Biological Networks: A Survey on Graph Classifying Techniques

    Mueller, Laurin A. J. (et al.)

    Pages 43-63

  • Emergent Properties of Gene Regulatory Networks: Models and Data

    Serra, Roberto (et al.)

    Pages 65-93

  • Regulatory Crosstalk Analysis of Biochemical Networks in the Hippocampus and Nucleus Accumbens

    Kikuchi, Shinichi (et al.)

    Pages 95-127

  • Properties of Biological Networks

    Dančík, Vlado (et al.)

    Pages 129-178

Buy this book

eBook $159.00
price for USA (gross)
  • ISBN 978-94-007-6803-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $209.00
price for USA
  • ISBN 978-94-007-6802-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
price for USA
  • ISBN 978-94-007-9454-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Systems Biology
Book Subtitle
Integrative Biology and Simulation Tools
Editors
  • Ales Prokop
  • Bela Csukas
Copyright
2013
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-007-6803-1
DOI
10.1007/978-94-007-6803-1
Hardcover ISBN
978-94-007-6802-4
Softcover ISBN
978-94-007-9454-2
Edition Number
1
Number of Pages
XXXI, 553
Topics