Advances in Experimental Medicine and Biology

Transcriptional and Translational Regulation of Stem Cells

Editors: Hime, Gary, Abud, Helen (Eds.)

  • Latest research in stem cell regulation
  • Stem cells from various species are discussed providing a unique overview of stem cell biology
  • The regulators of stem cells provide new candidates for disease therapy
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eBook $169.00
price for USA (gross)
  • ISBN 978-94-007-6621-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-94-007-6620-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: October 13, 2016
  • ISBN 978-94-024-0182-0
  • Free shipping for individuals worldwide
About this book

This volume describes the latest findings on transcriptional and translational regulation of stem cells. Both transcriptional activators and repressors have been shown to be crucial for the maintenance of the stem cell state. A key element of stem cell maintenance is repression of differentiation factors or developmental genes – achieved transcriptionally, epigenetically by the Polycomb complex, and post-transcriptionally by RNA-binding proteins and microRNAs. This volume takes two approaches to this topic – (1) illustrating the general principles outlined above through a series of different stem cell examples – embryonic, iPS and adult stem cells, and (2) describing several molecular families that have been shown to have roles in regulation of multiple stem cell populations.

Table of contents (19 chapters)

  • The Stem Cell State

    Hime, Gary R. (et al.)

    Pages 1-4

  • Induction of Pluripotency

    Heffernan, Corey (et al.)

    Pages 5-25

  • Germline Stem Cells and Their Regulation in the Nematode Caenorhabditis elegans

    Kershner, Aaron (et al.)

    Pages 29-46

  • Transcriptional and Post-transcriptional Regulation of Drosophila Germline Stem Cells and Their Differentiating Progeny

    White-Cooper, Helen (et al.)

    Pages 47-61

  • Stem Cells in the Drosophila Digestive System

    Zeng, Xiankun (et al.)

    Pages 63-78

Buy this book

eBook $169.00
price for USA (gross)
  • ISBN 978-94-007-6621-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-94-007-6620-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: October 13, 2016
  • ISBN 978-94-024-0182-0
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Transcriptional and Translational Regulation of Stem Cells
Editors
  • Gary Hime
  • Helen Abud
Series Title
Advances in Experimental Medicine and Biology
Series Volume
786
Copyright
2013
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-007-6621-1
DOI
10.1007/978-94-007-6621-1
Hardcover ISBN
978-94-007-6620-4
Softcover ISBN
978-94-024-0182-0
Series ISSN
0065-2598
Edition Number
1
Number of Pages
X, 371
Number of Illustrations and Tables
8 b/w illustrations, 53 illustrations in colour
Topics