NATO Science for Peace and Security Series A: Chemistry and Biology

Advancing Methods for Biomolecular Crystallography

Editors: Read, Randy, Urzhumtsev, Alexandre G., Lunin, Vladimir Y. (Eds.)

  • Contributions from acknowledged leaders in the Field
  • Presents methods currently at the forefront, and new emerging approaches
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eBook $89.95
price for USA (gross)
  • ISBN 978-94-007-6232-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
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  • Immediate eBook download after purchase
Hardcover $229.00
price for USA
  • ISBN 978-94-007-6231-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $119.00
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  • ISBN 978-94-007-6319-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This work presents a snapshot of the state of the art of modern biomolecular crystallography, from crystallisation through structure determination and even interactive presentation on the web.  Methods driving the latest automated structure determination pipelines are explained, as well as how to deal with problems such as crystal pathologies that still demand expert analysis.  These methods are illustrated through their application to problems of great biological interest, such as the molecular machinery underlying the complement pathway, the mechanism of action of monoamine oxidase inhibitors, and the structure of the eukaryotic ribosome.  Complementary approaches, such as neutron diffraction, small angle X-ray scattering, coherent diffraction and computational modelling, are also explored.

Table of contents (31 chapters)

  • The Zen of Model Anomalies – Correct Most of Them. Treasure the Meaningful Valid Few. Live Serenely with the Rest!

    Richardson, Jane S. (et al.)

    Pages 1-10

  • Total Chemical Protein Synthesis for the Determination of Novel X-ray Structures by Racemic Protein Crystallography

    Mandal, Kalyaneswar (et al.)

    Pages 11-22

  • Crystal Pathologies

    Yeates, Todd O.

    Pages 23-31

  • Crystallizing Membrane Proteins for Structure-Function Studies Using Lipidic Mesophases

    Caffrey, Martin

    Pages 33-46

  • Searching for Needles in Haystacks: Automation and the Task of Crystal Structure Determination

    McSweeney, Seán

    Pages 47-57

Buy this book

eBook $89.95
price for USA (gross)
  • ISBN 978-94-007-6232-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $229.00
price for USA
  • ISBN 978-94-007-6231-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $119.00
price for USA
  • ISBN 978-94-007-6319-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Advancing Methods for Biomolecular Crystallography
Editors
  • Randy Read
  • Alexandre G. Urzhumtsev
  • Vladimir Y. Lunin
Series Title
NATO Science for Peace and Security Series A: Chemistry and Biology
Copyright
2013
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-007-6232-9
DOI
10.1007/978-94-007-6232-9
Hardcover ISBN
978-94-007-6231-2
Softcover ISBN
978-94-007-6319-7
Series ISSN
1874-6489
Edition Number
1
Number of Pages
XIII, 362
Number of Illustrations and Tables
131 b/w illustrations
Topics