Tumor Dormancy and Cellular Quiescence and Senescence

Tumor Dormancy, Quiescence, and Senescence, Volume 1

Aging, Cancer, and Noncancer Pathologies

Editors: Hayat, M.A. (Ed.)

  • The only recently published book that explains the true nature of malignant and benign tumors, allowing correct diagnosis and treatment
  • Includes detailed information on therapies
  • Numerous color illustrations enhance the research papers
  • Discusses a multitude of cancer types in relation to tumor dormancy and senescence
see more benefits

Buy this book

eBook $219.00
price for USA (gross)
valid through November 5, 2017
  • ISBN 978-94-007-5958-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
valid through November 5, 2017
  • ISBN 978-94-007-5957-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

With a particular emphasis on tumor dormancy in breast, lung, prostate, and liver cancers, as well as in melanoma, this first volume of a new Springer series focuses on the interrelationship between biological processes of aging and tumors—both dormant and quiescent. With detail supplied by numerous international researchers at the forefront of cancer research, the book examines a host of differing aspects of the topic.

Featured contributions analyze the role of the quiescent state in regulating hematopoietic and muscle stem cells. They also explore the mediation, by the kinase, in the reversible quiescent state of a subset of ovarian, pancreatic, and colon cancers. The book includes key research on the molecular mechanisms underlying stress-induced cellular senescence, in addition to those governing the accumulation of reactive oxygen species, and the induction of premature senescence. It also provides information on suppressing cellular senescence in the most common, and most aggressive malignant primary brain tumor in humans, glioblastoma multiforme. With comprehensive and cutting-edge information on therapeutic interventions and on the correct diagnosis of relevant neoplasms, and with numerous color illustrations, this is the most up-to-date assessment of current medical knowledge in this crucial area of medical research.

Table of contents (26 chapters)

  • Dormancy, Quiescence, and Cellular Senescence

    Hayat, M. A.

    Pages 3-5

  • Is Tumor Dormancy Clinically Relevant?

    Hölzel, Dieter (et al.)

    Pages 7-21

  • Microenvironmental Influence on Breast Cancer Dormancy and Metastasis

    Nahas, George R. (et al.)

    Pages 23-33

  • Determination of Breast Cancer Dormancy: Analysis of Circulating Free DNA Using SNP 6.0 Arrays

    Shaw, Jacqui (et al.)

    Pages 35-50

  • Clonogenicity of Cultured Prostate Cancer Cells Is Controlled by Dormancy: Significance and Comparison with Cell Culture Models of Breast Cancer Cell Dormancy

    Tchénio, Thierry

    Pages 51-62

Buy this book

eBook $219.00
price for USA (gross)
valid through November 5, 2017
  • ISBN 978-94-007-5958-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
valid through November 5, 2017
  • ISBN 978-94-007-5957-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Tumor Dormancy, Quiescence, and Senescence, Volume 1
Book Subtitle
Aging, Cancer, and Noncancer Pathologies
Editors
  • M.A. Hayat
Series Title
Tumor Dormancy and Cellular Quiescence and Senescence
Series Volume
1
Copyright
2013
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-007-5958-9
DOI
10.1007/978-94-007-5958-9
Hardcover ISBN
978-94-007-5957-2
Edition Number
1
Number of Pages
XXIV, 324
Number of Illustrations and Tables
8 b/w illustrations, 35 illustrations in colour
Topics