Skip to main content
SpringerLink
Log in

Cilia and Nervous System Development and Function

  • Book
  • © 2013

Overview

Editors:
  1. Kerry L. Tucker

    1. , Anatomy and Cell Biology, University of Heidelberg, Heidelberg, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Tamara Caspary

    1. , Human Genetics, Emory University, Atlanta, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Only book to combine the explosive field of ciliary biology with a focus on the emergent roles of cilia for the central and peripheral nervous systems
  • All chapters written by researchers personally involved in cutting-edge advancements in the respective field
  • Comprehensive analysis of the multitude of roles played by the primary cilium in neurogenesis and neural function
  • Includes supplementary material: sn.pub/extras

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (9 chapters)

  1. Front Matter

    Pages i-xiii
    Download chapter PDF

  2. Primary and Motile Cilia: Their Ultrastructure and Ciliogenesis

    • Sigrid Hoyer-Fender
    Pages 1-53

  3. Primary Cilia, Sonic Hedgehog Signaling, and Spinal Cord Development

    • Laura E. Mariani, Tamara Caspary
    Pages 55-82

  4. Primary Cilia and Brain Development

    • Evangelia Tasouri, Marc August Willaredt, Kerry L. Tucker
    Pages 83-104

  5. Primary Cilia in Cerebral Cortex: Growth and Functions on Neuronal and Non-neuronal Cells

    • Matthew R. Sarkisian, Jon I. Arellano, Joshua J. Breunig
    Pages 105-129

  6. Primary Cilia and Inner Ear Sensory Epithelia

    • Cynthia M. Grimsley-Myers, Ping Chen
    Pages 131-163

  7. Neuronal Cilia and Obesity

    • Nicolas F. Berbari, Raymond C. Pasek, Bradley K. Yoder
    Pages 165-191

  8. Motile Cilia and Brain Function: Ependymal Motile Cilia Development, Organization, Function and Their Associated Pathologies

    • Nathalie Spassky
    Pages 193-207

  9. Primary Cilia and Brain Cancer

    • Shirui Hou, Young-Goo Han
    Pages 209-228

  10. Abnormalities of the Central Nervous System Across the Ciliopathy Spectrum

    • Kate Baker, Philip L. Beales
    Pages 229-273

  11. Back Matter

    Pages 275-277
    Download chapter PDF
Back to top

Keywords

About this book

Cilia are tiny microtubule-based organelles projecting from the plasma membrane of practically all cells in the body. In the past 10 years a flurry of research has indicated a crucial role of this long-neglected organelle in the development and function of the central nervous system. A common theme of these studies is the critical dependency of signal transduction of the Sonic hedgehog, and more recently, Wnt signaling pathways upon cilia to regulate fate decisions and morphogenesis. Both primary and motile cilia also play crucial roles in the function of the nervous system, including the primary processing of sensory information, the control of body mass, and higher functions such as behavior and cognition, serving as "antennae" for neurons to sense and process their environment. In this book we describe the structure and function of cilia and the various tissues throughout the brain and spinal cord that are dependent upon cilia for their proper development and function.

Editors and Affiliations

  • , Anatomy and Cell Biology, University of Heidelberg, Heidelberg, Germany

    Kerry L. Tucker

  • , Human Genetics, Emory University, Atlanta, USA

    Tamara Caspary

Bibliographic Information

Publish with us

Policies and ethics

Back to top

Search

Navigation