Cancer Metastasis - Biology and Treatment

Central Nervous System Metastasis, the Biological Basis and Clinical Considerations

Editors: Palmieri, Diane (Ed.)

  • Comprehensive resource of both biology and clinical knowledge of CNS metastasis
  • Only current book to cover the biology in depth, most cover clinical management of the disease
  • Topics covered by leaders in their respective fields
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Buy this book

eBook $169.00
price for USA (gross)
  • ISBN 978-94-007-5291-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-94-007-5290-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-94-017-8201-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume will cover what is known regarding the biology and treatment of CNS metastasis, including novel chapters such as the future of targeted therapies.  It will begin with an overview of the natural history and risk factors for CNS metastases that will broadly cover all cancer histologies.   This will be followed by 3 chapters that will cover the biology. These include: molecular biology, discussing what is known about specific genes/proteins involved in the process and model systems to study brain metastasis; the brain microenvironment, focusing on how it is different from the microenvironment of other organs of the body; and the blood-brain barrier,  which includes a discussion of permeability with respect to brain metastases.  A chapter on experimental imaging will cover both the biology of brain metastasis from an imaging perspective and use of imaging techniques to study brain metastases.  The clinical chapters will discuss treatment options with separate chapters on surgery, chemotherapy and radiation.  In addition, leptomeningeal metastasis will be given its own chapter.  Finally, quality of life issues will be the concluding chapter.

Reviews

From the reviews:

“This book reviews both the biology of central nervous system metastases and the basics of diagnosis and management. … The audience for this book is broad, in that it may attract both basic scientists and the clinicians. … the book is well written and easy to understand. … This is a book that I would value in my personal library. … I have not seen a book in this field with a similar breadth in covering both a scientific and clinical overview of CNS metastases.” (Priya U. Kumthekar, Doody’s Book Reviews, July, 2013)

Table of contents (11 chapters)

  • An Introduction to Brain Metastasis

    Palmieri, Diane

    Pages 1-13

  • The Molecular Biology of Brain Metastasis

    Woditschka, Stephan (et al.)

    Pages 15-41

  • The Brain Microenvironment

    Noda, Mami

    Pages 43-54

  • Vascular Permeability Within Brain Metastases

    Adkins, Chris E. (et al.)

    Pages 55-68

  • Imaging Experimental Brain Metastases

    Hamilton, Amanda M. (et al.)

    Pages 69-86

Buy this book

eBook $169.00
price for USA (gross)
  • ISBN 978-94-007-5291-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-94-007-5290-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-94-017-8201-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Central Nervous System Metastasis, the Biological Basis and Clinical Considerations
Editors
  • Diane Palmieri
Series Title
Cancer Metastasis - Biology and Treatment
Series Volume
18
Copyright
2012
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-007-5291-7
DOI
10.1007/978-94-007-5291-7
Hardcover ISBN
978-94-007-5290-0
Softcover ISBN
978-94-017-8201-2
Series ISSN
1568-2102
Edition Number
1
Number of Pages
XII, 228
Topics