Focus on Structural Biology

Identification of Ligand Binding Site and Protein-Protein Interaction Area

Editors: Roterman-Konieczna, Irena (Ed.)

  • Comparative analysis of models based on geometry versus those based on knowledge of the biological phenomenon Application note Relation to biological phenomena
  • All illustrations in full color
  • A review of the latest numerical techniques used to identify ligand binding and protein complexation sites
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eBook $169.00
price for USA (gross)
  • ISBN 978-94-007-5285-6
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Hardcover $219.00
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  • ISBN 978-94-007-5284-9
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Softcover $219.00
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  • ISBN 978-94-017-8284-5
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About this book

This volume presents a review of the latest numerical techniques used to identify ligand binding and protein complexation sites. It should be noted that there are many other theoretical studies devoted to predicting the activity of specific proteins and that useful protein data can be found in numerous databases. The aim of advanced computational techniques is to identify the active sites in specific proteins and moreover to suggest a generalized mechanism by which such protein-ligand (or protein-protein) interactions can be effected. Developing such tools is not an easy task – it requires extensive expertise in the area of molecular biology as well as a firm grasp of numerical modeling methods. Thus, it is often viewed as a prime candidate for interdisciplinary research.

Table of contents (7 chapters)

  • SuMo: A Tool for Protein Function Inference Based on 3D Structures Comparisons

    Chemelle, Julie-Anne (et al.)

    Pages 1-23

  • Identification of Pockets on Protein Surface to Predict Protein–Ligand Binding Sites

    Huang, Bingding

    Pages 25-39

  • Can the Structure of the Hydrophobic Core Determine the Complexation Site?

    Banach, Mateusz (et al.)

    Pages 41-54

  • Comparative Analysis of Techniques Oriented on the Recognition of Ligand Binding Area in Proteins

    Alejster, Paweł (et al.)

    Pages 55-86

  • Docking Predictions of Protein-Protein Interactions and Their Assessment: The CAPRI Experiment

    Janin, Joël

    Pages 87-104

Buy this book

eBook $169.00
price for USA (gross)
  • ISBN 978-94-007-5285-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-94-007-5284-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-94-017-8284-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Identification of Ligand Binding Site and Protein-Protein Interaction Area
Editors
  • Irena Roterman-Konieczna
Series Title
Focus on Structural Biology
Series Volume
8
Copyright
2013
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-007-5285-6
DOI
10.1007/978-94-007-5285-6
Hardcover ISBN
978-94-007-5284-9
Softcover ISBN
978-94-017-8284-5
Series ISSN
1571-4853
Edition Number
1
Number of Pages
X, 170
Topics