MicroRNAs as Tools in Biopharmaceutical Production

Editors: Barron, Niall (Ed.)

  • Biology of microRNAs for use as tools
  • Implementation of these molecules to improve processes in the Biopharmceutical field
  • Methods to implement these molecules in the Bioprocess setting
see more benefits

Buy this book

eBook $119.00
price for USA (gross)
  • ISBN 978-94-007-5128-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $159.00
price for USA
  • ISBN 978-94-007-5127-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $159.00
price for USA
  • ISBN 978-94-007-9526-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Focused manuscript on the potential use/role of miRNAs in bioprocessing, specifically the production of complex proteins in mammalian cells. With that in mind I propose a draft list of topics/chapters along the following lines: Intro on CHO/bioprocessing/engineering challenges to set scene, Genomic organization, biogenesis and mode of action, Identifying miRNA targets: Computational prediction, transcriptomics, proteomices, UTR analysis, etc., miRNA expression in Chinese Hamster Ovary cells,  miRNAs as engineering targets: pathway manipulation to impact bioprocess phenotypes, miRNAs as biomarkers, Detection methods: Northern, PCR, hybridization arrays, Next Gen Seq, Manipulation of expression in cultured cells: Transient/stable disregulation, Knockout.

Table of contents (8 chapters)

  • A General Introduction to MicroRNAs, Their Investigation and Exploitation in CHO Cell Lines

    Jossé, Lyne (et al.)

    Pages 1-13

  • Biogenesis of Mammalian miRNA

    Clarke, Stephen L. (et al.)

    Pages 15-27

  • Target Prediction Algorithms and Bioinformatics Resources for miRNA Studies

    Clarke, Colin (et al.)

    Pages 29-48

  • The CHO miRNA Transcriptome

    Hackl, Matthias (et al.)

    Pages 49-64

  • MicroRNAs as Engineering Targets: Pathway Manipulation to Impact Bioprocess Phenotypes

    Shiloach, Joseph (et al.)

    Pages 65-85

Buy this book

eBook $119.00
price for USA (gross)
  • ISBN 978-94-007-5128-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $159.00
price for USA
  • ISBN 978-94-007-5127-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $159.00
price for USA
  • ISBN 978-94-007-9526-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
MicroRNAs as Tools in Biopharmaceutical Production
Editors
  • Niall Barron
Copyright
2012
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-007-5128-6
DOI
10.1007/978-94-007-5128-6
Hardcover ISBN
978-94-007-5127-9
Softcover ISBN
978-94-007-9526-6
Edition Number
1
Number of Pages
X, 126
Topics