Heat Shock Proteins

Cellular Trafficking of Cell Stress Proteins in Health and Disease

Editors: Henderson, Brian, Pockley, A. Graham (Eds.)

  • The book is written by leaders in the field of heat shock protein research
  • This volume brings together experts in the biochemistry, cellular biology, immunology and molecular biology of molecular chaperones and Protein-Folding Catalysts (PFCs) with a focus on the mechanisms of cellular trafficking of these proteins and the role of these variegated trafficking mechanisms in both human and animal health and disease.
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  • The book contains focussed sections covering i) historical aspects of molecular chaperone biology, ii) Intracellular Trafficking of Molecular Chaperones and its Consequences, iii) Molecular Chaperones in Intracellular Trafficking and Function of Immune Receptors, iv) Molecular Chaperones as Cell Surface Receptors, and v) Extracellular Secretion of Molecular Chaperones
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eBook $189.00
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  • ISBN 978-94-007-4740-1
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  • Immediate eBook download after purchase
Hardcover $239.00
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  • ISBN 978-94-007-4739-5
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  • Usually dispatched within 3 to 5 business days.
Softcover $239.00
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  • ISBN 978-94-007-9590-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Since the beginning of the 21st Century there has been a rapid increase in our understanding of the cellular trafficking mechanisms of molecular chaperones in eukaryotes and in prokaryotes. In the former, molecular chaperone trafficking can occur between the various cellular compartments, with concomitant movement of other proteins. Such events can also result in the release of molecular chaperones from cells. In bacteria, molecular chaperones are involved in the trafficking of other proteins and are themselves released into the external milieu. The increasing appreciation of the role of molecular chaperones and Protein-Folding Catalysts in the interplay between bacteria and the cells of their hosts is now an important area of research for understanding the mechanisms of infectious diseases. This volume brings together experts in the biochemistry, cellular biology, immunology and molecular biology of molecular chaperones and Protein-Folding Catalysts with a focus on the mechanisms of cellular trafficking of these proteins and the role of these variegated trafficking mechanisms in both human and animal health and disease.

Table of contents (18 chapters)

  • Discovery of the Cellular Secretion of Cell Stress Proteins

    Hightower, Lawrence E. (et al.)

    Pages 1-11

  • Discovery of the Extracellular Agonist Actions of Molecular Chaperones and Protein-Folding Catalysts

    Henderson, Brian

    Pages 13-27

  • Molecular Chaperones and Protein-Folding Catalysts in Biological Fluids

    Pockley, A. Graham

    Pages 29-42

  • Hsp27 Phosphorylation Patterns and Cellular Consequences

    Moens, Ugo (et al.)

    Pages 43-74

  • Evidence on Cholesterol-Controlled Lipid Raft Interaction of the Small Heat Shock Protein HSPB11

    Török, Zsolt (et al.)

    Pages 75-85

Buy this book

eBook $189.00
price for USA (gross)
  • ISBN 978-94-007-4740-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $239.00
price for USA
  • ISBN 978-94-007-4739-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $239.00
price for USA
  • ISBN 978-94-007-9590-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Cellular Trafficking of Cell Stress Proteins in Health and Disease
Editors
  • Brian Henderson
  • A. Graham Pockley
Series Title
Heat Shock Proteins
Series Volume
6
Copyright
2012
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-007-4740-1
DOI
10.1007/978-94-007-4740-1
Hardcover ISBN
978-94-007-4739-5
Softcover ISBN
978-94-007-9590-7
Series ISSN
1877-1246
Edition Number
1
Number of Pages
XIV, 298
Topics