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DNA Repair of Cancer Stem Cells

Editors: Mathews, Lesley A, Cabarcas, Stephanie M., Hurt, Elaine (Eds.)

  • Currently there are no books solely available on DNA repair mechanisms and Cancer Stem Cells
  • This information can be used by academic institutions, pharmaceutical companies, medical professionals, government and biotechnology companies to aid in the drug discovery process against cancer stem cells
  • Experts in the fields of stem cells, cancer biology and DNA repair have come together to share their cutting edge knowledge on how to design drugs against these drug resistant cells Included is a chapter on how to screen for drugs to kill Cancer Stem Cells and attack their efficient DNA repair mechanisms
  • Wonderful text to teach from for an upper level college or graduate level classes on rational drug design
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eBook $169.00
price for USA (gross)
valid through October 16, 2017
  • ISBN 978-94-007-4590-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
valid through October 16, 2017
  • ISBN 978-94-007-4589-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-94-007-9705-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The existence of ‘cancer stem cells’ (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuous characterization in a variety of solid tumors has lead to an abundance of evidence supporting their existence. CSCs are believed to be responsible for resistance against conventional treatment regimes of chemotherapy and radiation, ultimately, leading to metastasis and patient demise. To help aid clinicians, pharmaceutical companies and academic labs investigating how to better kill these highly aggressive cells we have summarized the DNA repair mechanism(s) and their role in the maintenance and regulation of both normal and cancer stem cells. Our book represents a comprehensive investigation into the highly effective DNA repair mechanisms of CSCs and what we need to understand in order to develop more advanced therapies to eradicate them from patients. Currently, there are no other published works entirely on DNA repair and Cancer Stem Cells. In addition, our book provides a comprehensive overview of CSC isolation and characterization from a variety of solid tumor types.

Table of contents (10 chapters)

  • Introduction to Cancer Stem Cells

    Gao, Chengzhuo (et al.)

    Pages 1-18

  • DNA Repair Pathways and Mechanisms

    Dexheimer, Thomas S.

    Pages 19-32

  • Resistance and DNA Repair Mechanisms of Cancer Stem Cells: Potential Molecular Targets for Therapy

    Ahmad, Aamir (et al.)

    Pages 33-52

  • DNA Repair in Normal Stem Cells

    Momčilović, Olga (et al.)

    Pages 53-87

  • DNA Repair Mechanisms in Glioblastoma Cancer Stem Cells

    Venere, Monica (et al.)

    Pages 89-103

Buy this book

eBook $169.00
price for USA (gross)
valid through October 16, 2017
  • ISBN 978-94-007-4590-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
valid through October 16, 2017
  • ISBN 978-94-007-4589-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-94-007-9705-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
DNA Repair of Cancer Stem Cells
Editors
  • Lesley A Mathews
  • Stephanie M. Cabarcas
  • Elaine Hurt
Copyright
2013
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-007-4590-2
DOI
10.1007/978-94-007-4590-2
Hardcover ISBN
978-94-007-4589-6
Softcover ISBN
978-94-007-9705-5
Edition Number
1
Number of Pages
VIII, 180
Topics