Tumors of the Central Nervous System

Tumors of the Central Nervous System, Volume 8

Astrocytoma, Medulloblastoma, Retinoblastoma, Chordoma, Craniopharyngioma, Oligodendroglioma, and Ependymoma

Editors: Hayat, M.A. (Ed.)

  • New technologies and their applications in tumor diagnosis, treatment, and prognosis are discussed
  • Methods to assess the effectiveness of cancer treatments are presented
  • The importance of the quality of life after cancer therapy is pointed out
  • Molecular profiling of brain tumors to select targeted therapy in clinical trials is explained
  • A large number of color figures are included
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Hardcover $279.00
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  • ISBN 978-94-007-4212-3
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About this book

With tens of thousands of new CNS tumor cases each year in the US alone, this series of publications is a valuable aid to the diagnosis and treatment of these problematic neoplasms. Now, the eighth in the set returns to the topic of brain tumors, dealing with seven distinct types: astrocytoma, medulloblastoma, retinoblastoma, chordoma, craniopharyngioma, oligodendroglioma, and ependymoma. After updating the classification of medulloblastoma the volume provides an overview of ependymoma as well as describing the delineation of prognosis based on the genetic aberrations of the latter patients. The material offers key insights into the molecular pathways involved in tumor biology, such as the role of E-cadherin gene instability, carbonic anhydrase II, urokinase plasminogen activator, and Wnt signaling in meningioma. Contributors explain the genetic and clinical features associated with recurring meningioma, including the role played by erythropoietin receptor, and examine the way in which OTX2 transcription factor functions as an oncogene in medulloblastoma. With much more besides, including discussion of the molecular mechanisms that result in resistance to chemotherapy in medulloblastoma, this volume and its companions have a positive role to play in inspiring a new generation of researchers to design new drugs that are better targeted—and thus more effective.

Reviews

From the reviews:

“This volume in the series, Tumors of the Central Nervous System, explores recent developments in tumor biology and newer classification and treatment information for seven distinct types of brain tumors. … The book is written for oncologists, both fellows and practitioners, neuro-oncologists, neurologists, neuropathologists, and neurosurgeons. … In addition to providing an update, the book can also inspire a new generation of researchers in tumor biology and in the design of more effective and scientifically based chemotherapy.” (Ramsis Farid Ghaly, Doody’s Review Service, October, 2012)

Table of contents (33 chapters)

  • Astrocytoma Cell Line: Role of Brain Natriuretic Peptide

    Osanai, Tomohiro (et al.)

    Pages 3-11

  • Malignant Brain Astrocytomas: Extent of Resection Affects Survival

    Chaichana, Kaisorn L. (et al.)

    Pages 13-20

  • Medulloblastoma: Classification (A Review)

    Caracciolo, Valentina (et al.)

    Pages 23-33

  • Medulloblastomas: Clinically Important MicroRNA Genes

    Kamnasaran, Deepak

    Pages 35-46

  • Medulloblastoma: Role of OTX2 Transcription Factors

    Mattox, Austin (et al.)

    Pages 47-58

Buy this book

eBook $219.00
price for USA (gross)
  • ISBN 978-94-007-4213-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-94-007-4212-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the ebook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Tumors of the Central Nervous System, Volume 8
Book Subtitle
Astrocytoma, Medulloblastoma, Retinoblastoma, Chordoma, Craniopharyngioma, Oligodendroglioma, and Ependymoma
Editors
  • M.A. Hayat
Series Title
Tumors of the Central Nervous System
Series Volume
8
Copyright
2012
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media B.V.
eBook ISBN
978-94-007-4213-0
DOI
10.1007/978-94-007-4213-0
Hardcover ISBN
978-94-007-4212-3
Series ISSN
2215-096X
Edition Number
1
Number of Pages
XXXVII, 347
Topics