Subcellular Biochemistry

Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease

Editors: Harris, Tony J C (Ed.)

  • Up-to-date reviews of adherens junction biology from internationally recognized experts in the field
  • Covers adherens junction biology from atoms to overall animal development and disease
  • A comprehensive resource for the research laboratory
  • A comprehensive teaching tool for advanced undergraduate and graduate courses in cell and developmental biology
  • Valuable for both newcomers and experts in the field
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eBook $229.00
price for USA (gross)
  • ISBN 978-94-007-4186-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-94-007-4185-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-94-007-9616-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Cell–cell adhesion is fundamental for the development and homeostasis of animal tissues and organs. Adherens junctions (AJs) are the best understood cell-cell adhesion complexes. In this volume, a group of internationally recognized experts reviews AJ biology over a wide range of organization; from atoms to molecules, to protein complexes, molecular networks, cells, tissues, and overall animal development. AJs have also been an integral part of animal evolution, and play central roles in cancer development, pathogen infection and other diseases. This book addresses major questions encompassing AJ biology.
• How did AJs evolve?
• How do cadherins and catenins interact to assemble AJs and mediate adhesion?
• How do AJs interface with other cellular machinery to couple adhesion with the whole cell?
• How do AJs affect cell behaviour and multicellular development?
• How can abnormal AJ activity lead to disease?

Table of contents (18 chapters)

  • An Introduction to Adherens Junctions: From Molecular Mechanisms to Tissue Development and Disease

    Harris, Tony J. C.

    Pages 1-5

  • Evolution of the Cadherin–Catenin Complex

    Hiroki, Oda

    Pages 9-35

  • The Three-Dimensional Structure of the Cadherin–Catenin Complex

    Ishiyama, Noboru (et al.)

    Pages 39-62

  • Biophysics of Cadherin Adhesion

    Leckband, Deborah (et al.)

    Pages 63-88

  • Adherens Junction Assembly

    Troyanovsky, Sergey

    Pages 89-108

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-94-007-4186-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-94-007-4185-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-94-007-9616-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease
Editors
  • Tony J C Harris
Series Title
Subcellular Biochemistry
Series Volume
60
Copyright
2012
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-007-4186-7
DOI
10.1007/978-94-007-4186-7
Hardcover ISBN
978-94-007-4185-0
Softcover ISBN
978-94-007-9616-4
Series ISSN
0306-0225
Edition Number
1
Number of Pages
VI, 434
Topics