Computational Systems Neurobiology

Editors: Le Novère, N. (Ed.)

  • Covers the whole spectrum of computational modeling of neuronal systems, from the molecule to the organ
  • Contains several introductory chapters for newcomers, but also describes state of the art research
  • The book can be read as a whole but chapters can also be read in isolation
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Buy this book

eBook $169.00
price for USA (gross)
  • ISBN 978-94-007-3858-4
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-94-007-3857-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-94-017-8380-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Computational neurosciences and systems biology are among the main domains of life science research where mathematical modeling made a difference. This book introduces the many different types of computational studies one can develop to study neuronal systems. It is aimed at undergraduate students starting their research in computational neurobiology or more senior researchers who would like, or need, to move towards computational approaches. Based on their specific project, the readers would then move to one of the more specialized excellent textbooks available in the field. The first part of the book deals with molecular systems biology. Functional genomics is introduced through examples of transcriptomics and proteomics studies of neurobiological interest. Quantitative modelling of biochemical systems is presented in homogeneous compartments and using spatial descriptions. A second part deals with the various approaches to model single neuron physiology, and naturally moves to neuronal networks. A division is focused on the development of neurons and neuronal systems and the book closes on a series of methodological chapters. From the molecules to the organ, thinking at the level of systems is transforming biology and its impact on society. This book will help the reader to hop on the train directly in the tank engine.

Reviews

From the book reviews:

“This is an excellent reference on mathematical neurobiology at the single level, multiple level, and biophysical level. … This is a good neural modeling book which brings to light ideas concerning Bayes Theorems and NeuroML ensembles. I highly recommend it.” (Joseph J. Grenier, Amazon.com, July, 2014)


Table of contents (18 chapters)

  • Functional Genomics and Molecular Networks Gene Expression Regulations in Complex Diseases: Down Syndrome as a Case Study

    Potier, Marie-Claude (et al.)

    Pages 1-22

  • Reconstructing Models from Proteomics Data

    Zografos, Lysimachos (et al.)

    Pages 23-80

  • Using Chemical Kinetics to Model Neuronal Signalling Pathways

    Endler, Lukas (et al.)

    Pages 81-117

  • Breakdown of Mass-Action Laws in Biochemical Computation

    Santamaria, Fidel (et al.)

    Pages 119-132

  • Spatial Organization and Diffusion in Neuronal Signaling

    Brown, Sherry-Ann (et al.)

    Pages 133-161

Buy this book

eBook $169.00
price for USA (gross)
  • ISBN 978-94-007-3858-4
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-94-007-3857-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-94-017-8380-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Computational Systems Neurobiology
Editors
  • N. Le Novère
Copyright
2012
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-007-3858-4
DOI
10.1007/978-94-007-3858-4
Hardcover ISBN
978-94-007-3857-7
Softcover ISBN
978-94-017-8380-4
Edition Number
1
Number of Pages
VIII, 572
Topics