Overview
- Tissue regenaration
- Tissue transplantation
- Regenerative medicine
- Color illustrations
Part of the book series: Stem Cells and Cancer Stem Cells (STEM, volume 5)
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Table of contents (28 chapters)
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Front Matter
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Tissue Injury
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Front Matter
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Cardiovascular Applications
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Front Matter
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Keywords
About this book
It is pointed out that a cancer stem cell is a type within a tumor that possesses the capacity of self-renewal and can give rise to the heterogeneous lineages of cancer cells, which comprise the tumor. It is emphasized that a unique feature of cancer stem cells is that, although conventional chemotherapy kills most cells in a tumor, cancer stem cells remain intact. Vast applications of the following specific stem cells in disease and tissue injury are discussed: embryonic stem cells, human mesenchymal stem cells, cancer stem cells, arterial stem cells, neural stem cells, cardiac stem cells, dental stem cells, limbal stem cells, and hematopoietic stem cells. Because human embryonic stem cells possess the potential to produce unlimited quantities of any human cell type, considerable focus is placed on their therapeutic potential in this volume. These cells are used in tissue engineering, regenerative medicine, pharmacological and toxicological studies, and fundamental studies of cell differentiation. It is pointed out that the formation of embryoid bodies, which are three-dimensional aggregates of embryonic cells, is the initial step in the differentiation of these cells. Therapeutic implications of signalling pathways in cancer stem cells are pointed out. Targeting self-renewal pathways in cancer stem cells are also included. Application of mesenchymal stem cells for treating ischemic brain injury is explained. Neural stem cells proliferation into the surrounding area of the traumatic brain injury is explained.
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Editors and Affiliations
Bibliographic Information
Book Title: Stem Cells and Cancer Stem Cells, Volume 5
Book Subtitle: Therapeutic Applications in Disease and Injury
Editors: M.A. Hayat
Series Title: Stem Cells and Cancer Stem Cells
DOI: https://doi.org/10.1007/978-94-007-2900-1
Publisher: Springer Dordrecht
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media B.V. 2012
Hardcover ISBN: 978-94-007-2899-8Published: 22 February 2012
Softcover ISBN: 978-94-017-7934-0Published: 23 August 2016
eBook ISBN: 978-94-007-2900-1Published: 21 February 2012
Series ISSN: 2215-0994
Series E-ISSN: 2215-1001
Edition Number: 1
Number of Pages: XIX, 309
Topics: Cancer Research, Gene Expression, Laboratory Medicine, Neurosciences, Oncology, Pathology