Stem Cells and Cancer Stem Cells

Stem Cells and Cancer Stem Cells, Volume 5

Therapeutic Applications in Disease and Injury

Editors: Hayat, M.A. (Ed.)

  • Tissue regenaration
  • Tissue transplantation
  • Regenerative medicine
  • Cell therapy
  • Color illustrations
see more benefits

Buy this book

eBook $219.00
price for USA (gross)
  • ISBN 978-94-007-2900-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-94-007-2899-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

It is pointed out that a cancer stem cell is a type within a tumor that possesses the capacity of self-renewal and can give rise to the heterogeneous lineages of cancer cells, which comprise the tumor. It is emphasized that a unique feature of cancer stem cells is that, although conventional chemotherapy kills most cells in a tumor, cancer stem cells remain intact. Vast applications of the following specific stem cells in disease and tissue injury are discussed:  embryonic stem cells, human mesenchymal stem cells, cancer stem cells, arterial stem cells, neural stem cells, cardiac stem cells, dental stem cells, limbal stem cells, and hematopoietic stem cells.  Because human embryonic  stem cells possess the potential to produce unlimited quantities of any human cell type, considerable focus is placed on their therapeutic potential in this volume.  These cells are used in tissue engineering, regenerative medicine, pharmacological and  toxicological studies, and fundamental studies of cell differentiation. It is pointed out that the formation of embryoid bodies, which are three-dimensional aggregates of embryonic cells, is the initial step in the differentiation of these cells. Therapeutic implications of signalling pathways in cancer stem cells are pointed out.  Targeting self-renewal pathways in cancer stem cells are also included. Application of mesenchymal stem cells for treating ischemic brain injury is explained.  Neural stem cells proliferation into the surrounding area of the traumatic brain injury is explained.

 

Table of contents (28 chapters)

  • Signaling Pathways in Cancer Stem Cells: Therapeutic Implications

    Pastò, Anna (et al.)

    Pages 3-11

  • Inhibition of Telomerase with Imetelstat Causes Depletion of Cancer Stem Cells

    Nitta, Ryan (et al.)

    Pages 13-24

  • Targeting Self-renewal Pathways in Cancer Stem Cells

    Maugeri-Saccà, Marcello (et al.)

    Pages 25-36

  • Detection of Cancer Stem Cells Using AC133 Antibody

    Catalano, Veronica (et al.)

    Pages 37-43

  • Peripheral Nerve Regeneration After Traumatic Injury and Stem-Cell Therapy

    Oliveira, Júlia Teixeira (et al.)

    Pages 47-58

Buy this book

eBook $219.00
price for USA (gross)
  • ISBN 978-94-007-2900-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-94-007-2899-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Stem Cells and Cancer Stem Cells, Volume 5
Book Subtitle
Therapeutic Applications in Disease and Injury
Editors
  • M.A. Hayat
Series Title
Stem Cells and Cancer Stem Cells
Series Volume
5
Copyright
2012
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media B.V.
eBook ISBN
978-94-007-2900-1
DOI
10.1007/978-94-007-2900-1
Hardcover ISBN
978-94-007-2899-8
Series ISSN
2215-0994
Edition Number
1
Number of Pages
XIX, 309
Topics