Stem Cells and Cancer Stem Cells

Stem Cells and Cancer Stem Cells, Volume 4

Therapeutic Applications in Disease and Injury

Editors: Hayat, M.A. (Ed.)

  • Tissue engineering is explained in detail
  • Role of regenerative medicine in therapy
  • Stem cell transplantation to heal tissue injury
  • Target medicine Translational medicine
  • Role of cancer stem cells in disease such as breast cancer
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eBook $219.00
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  • ISBN 978-94-007-2828-8
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  • Immediate eBook download after purchase
Hardcover $279.00
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  • ISBN 978-94-007-2827-1
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About this book

Vast therapeutic applications of the following specific stem cells in disease and tissue injury are discussed: embryonic stem cells, induced pluripotent stem cells, human hair follicle stem cells, bone marrow-derived human mesenchymal stem cells, adipose-derived stem cells, periodontal/progenitor cells, cancer stem cells, and breast cancer stem cells. Because human embryonic stem cells possess the potential to produce unlimited quantities of any human cell type, considerable focus is placed on this type of stem cells in this volume. The role of cancer stem cells, specifically in breast cancer is explained. Transplantation of mesenchymal stem cells to aid the injured brain is included. Immune recovery after stem cells transplantation in severe combined immunodeficiency patients is described. The role of mesenchymal stem cells in enhancing the growth and metastasis of colon cancer is discussed. Clinical application of human follicle stem cells is presented. Treatment of malignant gliomas using genetically-modified neural stem cells as a marker is discussed. The impact of cancer stem cell hypothesis on designing new cancer therapies is explained. In the field of regenerative medicine, the use of stem cells in the repair of the central nervous system, tendon injury, and as a cardiac regenerative medicine is described. The role of DNA methylation in maintaining stemness induced pluripotent stem cells from human extraembryonic amnion cells is discussed. Insights on the understanding of molecular pathways involved in tumor biology are explained, which lead to the development of effective drugs. Information on pathways, such as hedgehog, facilitates targeted therapies in cancer.

Table of contents (26 chapters)

  • Neural Stem/Progenitor Cell Proliferation and Differentiation: Role of Sonic Hedgehog and Wingless/Int-1 Proteins

    Anderova, Miroslava (et al.)

    Pages 3-18

  • Sensitivity of Hematopoietic and Leukemic Stem Cells to Hoxa Gene Levels

    Lebert-Ghali, Charles-Etienne (et al.)

    Pages 19-29

  • Maintenance of Neural Stem Cells in the Brain: Role of Notch Signaling

    Kageyama, Ryoichiro (et al.)

    Pages 31-39

  • Maintenance of Hematopoiesis: Role of Early B Cell Factor 2

    Kieslinger, Matthias

    Pages 41-50

  • Differentiation of Periodontal Ligament Stem/Progenitor Cells: Roles of TGF-β1

    Maeda, Hidefumi (et al.)

    Pages 51-58

Buy this book

eBook $219.00
price for USA (gross)
  • ISBN 978-94-007-2828-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-94-007-2827-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Stem Cells and Cancer Stem Cells, Volume 4
Book Subtitle
Therapeutic Applications in Disease and Injury
Editors
  • M.A. Hayat
Series Title
Stem Cells and Cancer Stem Cells
Series Volume
4
Copyright
2012
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media B.V.
eBook ISBN
978-94-007-2828-8
DOI
10.1007/978-94-007-2828-8
Hardcover ISBN
978-94-007-2827-1
Series ISSN
2215-0994
Edition Number
1
Number of Pages
XIX, 319
Topics