Epigenetic Epidemiology

Editors: Michels, Karin B. (Ed.)

  • First book in this new, emerging field
  • State of the art on human evidence in epigenetics
  • Helps to digest rapid growing information on epigenetics in humans
  • A guide how to design a study on epigenetics in humans
  • Assists in interpreting and understanding epigenetic evidence in humans
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Buy this book

eBook $189.00
price for USA (gross)
  • ISBN 978-94-007-2495-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $239.00
price for USA
  • ISBN 978-94-007-2494-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $239.00
price for USA
  • ISBN 978-94-007-9676-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance.  Epigenetics plays an  important role in shaping who we are and contributes to our prospects of health and disease.  While early epigenetic research focused on plant and animal models and in vitro experiments, population-based epidemiologic studies increasingly incorporate epigenetic components.  The relevance of epigenetic marks, such as DNA methylation, genomic imprinting, and histone modification for disease causation has yet to be fully explored. This book covers the basic concepts of epigenetic epidemiology, discusses challenges in study design, analysis, and interpretation, epigenetic laboratory techniques, the influence of of age and environmental factors on shaping the epigenome, the role of epigenetics in the developmental origins hypothesis, and provides the state of the art on the epigenetic epidemiology of various health conditions including childhood syndromes, cancer, infectious diseases, inflammation and rheumatoid arthritis, asthma, autism and other neurodevelopmental disorders, psychiatric disorders, diabetes, obesity and metabolic disorders, and atherosclerosis.

With contributions from: Peter Jones, Jean-Pierre Issa, Gavin Kelsey, Robert Waterland, and many other experts in epigenetics!

Reviews

From the reviews:

“It aims to be both a primer in epidemiology for epigeneticists and an epigenetics reference for epidemiologists. … the field of epigenetic epidemiology is in ascendency and this textbook provides the first broad foundation for anyone embarking on population-based studies in epigenetic epidemiology. … Any prospective researcher aspiring to address any of the many unanswered fundamental issues in this field would certainly find this book a must useful reference.” (Catherine Potter and Caroline L. Relton, International Journal of Epidemiology, Vol. 41 (1), February, 2012)

Table of contents (21 chapters)

  • Introduction

    Michels, Karin B.

    Pages 1-3

  • The Human Epigenome

    Jones, Peter A. (et al.)

    Pages 5-20

  • Considerations in the Design, Conduct, and Interpretation of Studies in Epigenetic Epidemiology

    Michels, Karin B.

    Pages 21-35

  • Laboratory Methods in Epigenetic Epidemiology

    Barault, Ludovic (et al.)

    Pages 37-56

  • Biostatistical Methods in Epigenetic Epidemiology

    Houseman, E. Andrés

    Pages 57-76

Buy this book

eBook $189.00
price for USA (gross)
  • ISBN 978-94-007-2495-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $239.00
price for USA
  • ISBN 978-94-007-2494-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $239.00
price for USA
  • ISBN 978-94-007-9676-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Epigenetic Epidemiology
Editors
  • Karin B. Michels
Copyright
2012
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media B.V.
eBook ISBN
978-94-007-2495-2
DOI
10.1007/978-94-007-2495-2
Hardcover ISBN
978-94-007-2494-5
Softcover ISBN
978-94-007-9676-8
Edition Number
1
Number of Pages
XII, 448
Topics