Cell Engineering

Antibody Expression and Production

Editors: Al-Rubeai, Mohamed (Ed.)

  • Detailed background for antibody generation and production
  • Chapters on production of antibody in bacterial, fungal, mammalian, insects and transgenic animal and plants
  • Scientific and technical approaches to accelerating the development of robust upstream and downstream processes
  • Identify the limitations in developing processes for antibody production
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eBook $229.00
price for USA (gross)
  • ISBN 978-94-007-1257-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-94-007-1256-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-94-007-3613-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Engineered antibodies currently represent over 30% of biopharmaceuticals in clinical trials and their total worldwide sales continue to increase significantly. The importance of antibody applications is reflected in their increasing clinical and industrial applications as well as in the progression of established and emerging production strategies. This volume provides detailed coverage of the generation, optimization, characterization, production and applications of antibody. It provides the necessary theoretical background and description of methods for the expression of antibody in microbial and animal cell cultures and in transgenic animals and plants. There is a strong focus on those issues related to the production of intrabodies, bispecific antibody and antibody fragments and also to novel applications in cancer immunotherapy.

Table of contents (14 chapters)

  • Expression of Antibody in Mammalian Cells

    Jostock, Thomas

    Pages 1-24

  • Bioreactor Systems for Producing Antibody from Mammalian Cells

    Kuystermans, Darrin (et al.)

    Pages 25-52

  • Production of Antibody in Insect Cells

    Yamaji, Hideki

    Pages 53-76

  • Production of Monoclonal Antibodies in Glycoengineered Pichia pastoris

    Zha, Dongxing (et al.)

    Pages 77-98

  • Production of Antibodies in Hansenula polymorpha

    Melmer, Georg (et al.)

    Pages 99-119

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-94-007-1257-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-94-007-1256-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-94-007-3613-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Antibody Expression and Production
Editors
  • Mohamed Al-Rubeai
Series Title
Cell Engineering
Series Volume
7
Copyright
2011
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media B.V.
eBook ISBN
978-94-007-1257-7
DOI
10.1007/978-94-007-1257-7
Hardcover ISBN
978-94-007-1256-0
Softcover ISBN
978-94-007-3613-9
Series ISSN
1389-6946
Edition Number
1
Number of Pages
X, 346
Topics