Tumors of the Central Nervous System

Tumors of the Central Nervous System, Volume 2

Gliomas: Glioblastoma (Part 2)

Editors: Hayat, M.A. (Ed.)

  • Emphasizes targeted therapy determined by molecular genetics
  • Details several imaging techniques for diagnosis and treatment assessment
  • Describes both current and future therapeutic drugs against malignant gliomas
  • Explains the anti-tumor action of cyclosporine A and functionally-related drugs
  • Covers the topics of brain tumor angiogenesis and glioma grading
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eBook $219.00
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  • ISBN 978-94-007-0618-7
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Hardcover $279.00
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  • ISBN 978-94-007-0617-0
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  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
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  • ISBN 978-94-007-3580-4
  • Free shipping for individuals worldwide
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About this book

Advantages and limitations of biomarkers in gliomagenesis are described. Molecular subtypes of gliomas are detailed. The role played by TP53 gene mutation in the deadliest brain tumor, glioblastoma multiforme, is pointed out. The role of mutations of IDH1 and IDH2, and isocitrate dehydrogenases in malignant gliomas are presented. Metabolic differences in different regions of the glioma tumor are clarified. Various types of imaging modalities, including PET and SPECT, to diagnose gliomas in general and glioblastoma in particular in patients are explained in detail. Both low-grade and high-grade gliomas are discussed. Conventional as well as fluorescent-guided resection techniques for high-grade, recurrent malignant gliomas are detailed. Impact of resection extent on outcomes in patients with high-grade gliomas is clarified. The advantage of the use of intraoperative low-field MRI in glioma surgery is explained.

Table of contents (42 chapters)

  • Introduction

    Hayat, M.A.

    Pages 1-7

  • Gliomagenesis: Advantages and Limitations of Biomarkers

    Wager, Michel (et al.)

    Pages 11-24

  • Molecular Subtypes of Gliomas

    Gravendeel, Lonneke A.M. (et al.)

    Pages 25-29

  • Glioblastoma: Germline Mutation of TP53

    Sugimura, Haruhiko (et al.)

    Pages 31-38

  • Familial Gliomas: Role of TP53 Gene

    Hallani, Soufiane El (et al.)

    Pages 39-45

Buy this book

eBook $219.00
price for USA (gross)
  • ISBN 978-94-007-0618-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-94-007-0617-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
price for USA
  • ISBN 978-94-007-3580-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Tumors of the Central Nervous System, Volume 2
Book Subtitle
Gliomas: Glioblastoma (Part 2)
Editors
  • M.A. Hayat
Series Title
Tumors of the Central Nervous System
Series Volume
2
Copyright
2011
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media B.V.
eBook ISBN
978-94-007-0618-7
DOI
10.1007/978-94-007-0618-7
Hardcover ISBN
978-94-007-0617-0
Softcover ISBN
978-94-007-3580-4
Series ISSN
2215-096X
Edition Number
1
Number of Pages
XXII, 458
Topics