Advances in Nuclear Architecture

Editors: Adams, Niall M., Freemont, Paul S. (Eds.)

  • Provides state-of-the-art reviews from top researchers
  • Presents a balanced emphasis on biological insight and quantitative analysis
  • First book on nuclear architecture that emphasizes quantitative analysis
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eBook $199.00
price for USA (gross)
  • ISBN 978-90-481-9899-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $259.00
price for USA
  • ISBN 978-90-481-9898-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $259.00
price for USA
  • ISBN 978-94-007-9809-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book provides a snapshot of the state-of-the art in the study of mammalian cell nuclear architecture, and features a diverse range of chapters written by top researchers. A key aspect is an emphasis on precise and repeatable quantitative analysis and simulation in addition to the more familiar biological perspective. The fusion of such material frames the future of the discipline. Quantitative contributions stress reproducible and robust 3D analysis, using a variety of tools ranging from point pattern analysis to shape registration methods. Biological insights include the role of nuclear subdomains in cancer, nuclear molecular motors, and a holistic view of gene transcription.

Table of contents (7 chapters)

  • Nuclear Subdomains and Cancer

    Cann, Kendra L. (et al.)

    Pages 1-58

  • Spatial Point Process Analysis of Promyelocytic Leukemia Nuclear Bodies

    Umande, Philip P. (et al.)

    Pages 59-85

  • Quantitative Approaches to Nuclear Architecture Analysis and Modelling

    H├╝bschmann, Daniel (et al.)

    Pages 87-129

  • Statistical Shape Theory and Registration Methods for Analyzing the 3D Architecture of Chromatin in Interphase Cell Nuclei

    Yang, Siwei (et al.)

    Pages 131-147

  • Nuclear Molecular Motors for Active, Directed Chromatin Movement in Interphase Nuclei

    Bridger, Joanna M. (et al.)

    Pages 149-172

Buy this book

eBook $199.00
price for USA (gross)
  • ISBN 978-90-481-9899-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $259.00
price for USA
  • ISBN 978-90-481-9898-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $259.00
price for USA
  • ISBN 978-94-007-9809-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Advances in Nuclear Architecture
Editors
  • Niall M. Adams
  • Paul S. Freemont
Copyright
2011
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media B.V.
eBook ISBN
978-90-481-9899-3
DOI
10.1007/978-90-481-9899-3
Hardcover ISBN
978-90-481-9898-6
Softcover ISBN
978-94-007-9809-0
Edition Number
1
Number of Pages
VII, 210
Topics