Sarcopenia – Age-Related Muscle Wasting and Weakness

Mechanisms and Treatments

Editors: Lynch, Gordon S. (Ed.)

  • State-of-the-art information on aging and skeletal muscle
  • Contributions from some of the world’s leading experts in skeletal muscle aging
  • Identifies key neuromuscular mechanisms responsible for sarcopenia
  • Identifies signalling pathways and targets for therapeutic intervention
  • Information has relevance and broad application for researchers and practitioners involved with the study and treatment of aging and its effects on skeletal muscle
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eBook $219.00
price for USA (gross)
  • ISBN 978-90-481-9713-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-90-481-9712-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
price for USA
  • ISBN 978-94-007-9044-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the developed world. There is an urgent need to better understand the neuromuscular mechanisms underlying age-related muscle wasting and to develop therapeutic strategies that can attenuate, prevent, or ultimately reverse sarcopenia. Significant research and development in academic and research institutions and in pharmaceutical companies is being directed to sarcopenia and to related health issues in order to develop and evaluate novel therapeutics. This book provides the latest information on sarcopenia from leading international researchers studying the cellular and molecular mechanisms underlying age-related changes in skeletal muscle and identifies strategies to combat sarcopenia and related muscle wasting conditions and neuromuscular disorders. The book provides a vital resource for researchers and practitioners alike, with information relevant to gerontologists, geriatricians, sports medicine physicians, physiologists, neuroscientists, cell biologists, endocrinologists, physical therapists, allied health and musculoskeletal practitioners, strength and conditioning specialists, athletic trainers, and students of the medical and biomedical sciences.

Table of contents (19 chapters)

  • Overview of Sarcopenia

    Lynch, Gordon S.

    Pages 1-7

  • Muscle Wasting in Cancer and Ageing: Cachexia Versus Sarcopenia

    Argilés, Josep M. (et al.)

    Pages 9-35

  • Age-Related Remodeling of Neuromuscular Junctions

    Mantilla, Carlos B. (et al.)

    Pages 37-54

  • Aging-Related Changes Motor Unit Structure and Function

    Cristea, Alexander (et al.)

    Pages 55-74

  • Age-Related Decline in Actomyosin Structure and Function

    Thompson, LaDora V.

    Pages 75-111

Buy this book

eBook $219.00
price for USA (gross)
  • ISBN 978-90-481-9713-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-90-481-9712-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
price for USA
  • ISBN 978-94-007-9044-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Sarcopenia – Age-Related Muscle Wasting and Weakness
Book Subtitle
Mechanisms and Treatments
Editors
  • Gordon S. Lynch
Copyright
2011
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media B.V.
eBook ISBN
978-90-481-9713-2
DOI
10.1007/978-90-481-9713-2
Hardcover ISBN
978-90-481-9712-5
Softcover ISBN
978-94-007-9044-5
Edition Number
1
Number of Pages
XIII, 479
Topics