Skip to main content
  • Book
  • © 2007

Heat Shock Proteins: Potent Mediators of Inflammation and Immunity

  • Contains chapters written by leaders in the field of heat shock protein (HSP) immunobiology
  • Covers in depth new mechanisms by which heat shock proteins modulate the hosts immune response
  • Subjects covered follow a logical sequence for activation of immune responses
  • Making it easy for even lay people to follow; binding and receptors to mechanisms of release to antigen processing and presentation to immune responses

Part of the book series: Heat Shock Proteins (HESP, volume 1)

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (21 chapters)

  1. Front Matter

    Pages I-XII
  2. Mechanisms of Heat Shock Protein Release

    1. Front Matter

      Pages 1-1
    2. Mechanisms of Stress-Induced Cellular Hsp72 Release

      • Graeme I. Lancaster, Mark A. Febbraio
      Pages 31-37
    3. Roles of Extracellular Heat Shock Proteins: A New Sense of Danger

      • John H.H. Williams, Claire Hunter-Lavin
      Pages 39-57
  3. Heat Shock Protein Binding and Receptor-Mediated Signaling

    1. Front Matter

      Pages 59-59
    2. Macrophages and the Stress Response

      • Virginia L. Vega, Antonio De Maio
      Pages 61-73
    3. Heat Shock Proteins and Scavenger Receptors

      • Yves Delneste, Sébastien Jaillon, Pascale Jeannin
      Pages 75-94
    4. The Inside Story: Anti-Inflammatory roles of HSF1 and heat shock proteins

      • Stuart K Calderwood, Xianzhong Xiao, Yue Xie
      Pages 95-113
    5. Interaction of Heat Shock Protein 60 with Innate Immune Cells

      • Christiane Habich, Volker Burkart
      Pages 115-128
  4. Immune Responses Elicited by Heat Shock Proteins

    1. Front Matter

      Pages 129-129
    2. HSP-APC Interactions: Initiation of Immune Responses

      • Robert J. Binder, Pramod K. Srivastava
      Pages 131-145
    3. Hsp-Induced Stimulation of Immune Responses

      • Thomas Lehner, Yufei Wang, Trevor Whittall, Lesley A. Bergmeier, Kaboutar Babaahmady, Charles Kelly
      Pages 159-172
    4. The Role of Heat Shock Proteins in the Elicitation of Immune Responses

      • Charles A Gullo, Paul Macary, Michael Graner
      Pages 173-187
    5. Hsp70 Family Members, Danger Signals and Autoimmunity

      • Douglas G. Millar, Pamela S. Ohashi
      Pages 189-211
    6. The Immune Response Under Stress: Class I HLA Presentation of Host-Derived Peptides

      • Angela Wahl, Oriana Hawkins, Curtis Mcmurtrey, Heather Hickman-Miller, Jon Weidanz, William Hildebrand
      Pages 213-234
    7. Extracellular Hsp 72: A Double-Edged Sword for Host Defense

      • Monika Fleshner, John D. Johnson, Joshua Friedman
      Pages 235-263
    8. HSP60: A Pleiotropic Immune Signal

      • Alexandra Zanin-Zhorov, Irun R. Cohen
      Pages 265-272

About this book

Heat Shock Proteins: Potent Mediators of Inflammation and Immunity currently provides the most up-to-date review on new mechanisms and provides exciting insights into how heat shock proteins modulates the hosts immune response. Written by leaders in the field of heat shock protein immunobiology, the chapters systematically and in a step wise fashion takes the reader through the fascinating sequence of events by which heat shock proteins activate immune responses and provides answers as to its biological significance to the host. From the early stages of binding and receptors-mediated signalling, to new paradigms by which heat shock proteins are released into the circulation, to antigen processing and presentation, and finally to the immune response itself this book is a must read for graduate and postgraduates in the field of Biology (plant and mammal), Biochemistry (pro- and eukaryotic), Immunology, Microbiology, Exercise Medicine, Physiology, Inflammatory diseases, Autoimmunity, Pharmacology and Pathology.

Editors and Affiliations

  • Effie and Wofford Cain Centennial Endowed Chair in Clinical Pathology, Chief, Division of Investigative Pathology Scott & White Memorial Hospital and Clinic and The Texas A&M University System Health Science Center College of Medicine Temple, TX, U.S.A

    Alexzander A. A. Asea

  • Department of Surgery, School of Medicine, University of California, San Diego, U.S.A

    Antonio De Maio

Bibliographic Information

  • Book Title: Heat Shock Proteins: Potent Mediators of Inflammation and Immunity

  • Editors: Alexzander A. A. Asea, Antonio De Maio

  • Series Title: Heat Shock Proteins

  • DOI: https://doi.org/10.1007/978-1-4020-5585-0

  • Publisher: Springer Dordrecht

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media B.V. 2007

  • Hardcover ISBN: 978-1-4020-5584-3Published: 29 June 2007

  • Softcover ISBN: 978-90-481-7401-0Published: 30 November 2010

  • eBook ISBN: 978-1-4020-5585-0Published: 05 September 2007

  • Series ISSN: 1877-1246

  • Series E-ISSN: 1877-1254

  • Edition Number: 1

  • Number of Pages: XII, 357

  • Topics: Immunology, Molecular Medicine, Cancer Research, Laboratory Medicine

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access