175 years of Springer publishing +++ Through June 30: 50% off Physics & Astronomy Books

Comparative Biology of Aging

Editors: Wolf, Norman S. (Ed.)

  • Offers a comprehensive examination of the comparative biology of aging
  • Compares as many species as possible for the biological and molecular changes that occur with aging
  • Discusses aging changes in various cells tissues and organs as well as the regimens and treatments that delay or accelerate their aging
  • Broadly focused, both from a multi-species approach and a multi-tissue approach
  • Covers both cell and organelle aging as well as full systemic changes
  • The contributing chapter authors are experts in their fields
see more benefits

Buy this book

eBook $219.00
price for USA (gross)
  • ISBN 978-90-481-3465-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-90-481-3464-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
price for USA
  • ISBN 978-94-007-9083-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Cover copy: Wolf, Norman (ed.), The Comparative Biology of Aging

The processes of aging and death remain one of the most fascinating, and mysterious, areas of biological research. Huge anomalies between species raise questions the answers to which could have fundamental implications for the field of medical science. As scientists unlock the secrets of the exceptionally long-lived little brown bat (up to 34 years), or the common Budgerigar which despite having a metabolic rate 1.5 times that of a laboratory mouse, can live for up to 20 years, it has become more important than ever to be able to make a comparative analysis of the various species used in research.

Dealing with every one of the species that are employed in laboratory research, this is the first book on the subject of aging that provides detailed comparative data for age-related changes in its subjects. It does so at the level of the whole animal, its organs, organelles and molecules. The comparative data, supplied in 15 chapters by leading experts, provides information on fields as disparate as telomere function and loss, the importance of the Sirtuins and Tor, the influence of hormones on lifespans, the relationship between body size and lifespan, the effects of restricted calorific intake, age-related changes in cell replication, and DNA damage and repair. Chapters are devoted to cardiac aging, comparative skeletal muscle aging, the aging of the nervous and immune systems, the comparative biology of lyosomal function and how it is affected by age, and many other key areas of research.

This much-needed text will provide scientists working in a wide spectrum of fields with key data to aid them in their studies.

Table of contents (15 chapters)

  • Introduction: Lifespans and Pathologies Present at Death in Laboratory Animals

    Wolf, Norman S. (et al.)

    Pages 1-26

  • Animal Size, Metabolic Rate, and Survival, Among and Within Species

    Austad, Steven N.

    Pages 27-41

  • Hormonal Influences on Aging and Lifespan

    Spong, Adam (et al.)

    Pages 43-68

  • Exploring Mechanisms of Aging Retardation by Caloric Restriction: Studies in Model Organisms and Mammals

    Anderson, Rozalyn M. (et al.)

    Pages 69-96

  • Cell Replication Rates In Vivo and In Vitro and Wound Healing as Affected by Animal Age, Diet, and Species

    Wolf, Norman S.

    Pages 97-122

Buy this book

eBook $219.00
price for USA (gross)
  • ISBN 978-90-481-3465-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-90-481-3464-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
price for USA
  • ISBN 978-94-007-9083-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Comparative Biology of Aging
Editors
  • Norman S. Wolf
Copyright
2010
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media B.V.
eBook ISBN
978-90-481-3465-6
DOI
10.1007/978-90-481-3465-6
Hardcover ISBN
978-90-481-3464-9
Softcover ISBN
978-94-007-9083-4
Edition Number
1
Number of Pages
IX, 391
Topics