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  • Book
  • © 2010

Mechanosensitivity of the Heart

  • This is the first series of books that considers the problem of cell mechanosensitivity of organs and tissues at the molecular, biological, bio-physical, physiological and pharmacological levels and draws the attention to the global problem of the mechanosensitivity and its mechanisms
  • In addition, the problem of intracellular crosstalk (i.e. a network of mechanically induced intracellular signaling cascades) is discussed for the first time

Part of the book series: Mechanosensitivity in Cells and Tissues (MECT, volume 3)

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xxxix
  2. Molecular Mechanisms of Mechanotransduction in Cardiac Cells

    1. Front Matter

      Pages 1-1
    2. Molecular Signaling Mechanisms of Myocardial Stretch: Implications for Heart Disease

      • Hind Lal, Suresh K. Verma, Honey B. Golden, Donald M. Foster, April M. Holt, David E. Dostal
      Pages 55-81
  3. Mechanically Induced Potentials and Currents of the Cardiac Cells in Healthy and Diseased Myocardium

    1. Front Matter

      Pages 97-97
    2. Mechanostransduction in Cardiac and Stem-Cell Derived Cardiac Cells

      • Jeffrey G. Jacot, Anna J. Raskin, Jeffrey H. Omens, Andrew D. McCulloch, Leslie Tung
      Pages 99-139
    3. Effects of Applied Stretch on Native and Recombinant Cardiac Na+ Currents

      • Umberto Banderali, Robert B. Clark, Catherine E. Morris, Martin Fink, Wayne R. Giles
      Pages 169-184
  4. Mechano-Electric Feedback in the Whole Heart and a Computer Simulation Study

    1. Front Matter

      Pages 272-272
    2. The Contribution of MEF to Electrical Heterogeneity and Arrhythmogenesis

      • David A. Saint, Douglas Kelly, Lorraine Mackenzie
      Pages 275-300
    3. Mechanical Modulation of a Reentrant Arrhythmia: The Atrial Flutter Case

      • Flavia Ravelli, Michela Masè
      Pages 301-325
    4. Early Hypertrophic Signals After Myocardial Stretch. Role of Reactive Oxygen Species and the Sodium/Hydrogen Exchanger

      • Horacio E. Cingolani, Néstor G. Pérez, Claudia I. Caldiz, Carolina D. Garciarena, Verónica C. De Giusti, María V. Correa et al.
      Pages 327-371
    5. Stretch-Induced Inotropy in Atrial and Ventricular Myocardium

      • Dirk von Lewinski, Jens Kockskämper, Mounir Khafaga, Robert Gasser, Burkert Pieske
      Pages 373-385
    6. Effects of Wall Stress on the Dynamics of Ventricular Fibrillation: A Computer Simulation Study of Mechanoelectric Feedback

      • Satoko Hirabayashi, Masashi Inagaki, Toshiaki Hisada, Masaru Sugimachi
      Pages 387-419
    7. Electromechanical Modelling of Cardiac Tissue

      • C. Cherubini, S. Filippi, P. Nardinocchi, L. Teresi
      Pages 421-449

Editors and Affiliations

  • Dept. Fundamental &, Russian State Medical University, Moskva, Russian Federation

    Andre Kamkin, Irina Kiseleva

Bibliographic Information

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access