SEMA SIMAI Springer Series

New Challenges for Cancer Systems Biomedicine

Editors: D'Onofrio, Alberto, Cerrai, Paola, Gandolfi, Alberto (Eds.)

  • State of the art in tumor modelling
  • It stresses the role of biomedical scientists working in modelling
  • Original interdisciplinary insight into the biomedical applications
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eBook $109.00
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  • ISBN 978-88-470-2571-4
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Hardcover $139.00
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  • ISBN 978-88-470-2570-7
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Softcover $139.00
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  • ISBN 978-88-470-5617-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The future of oncology seems to lie in Molecular Medicine (MM). MM is a new science based on three pillars. Two of them are evident in its very name and are well known: medical science and molecular biology. However, there is a general unawareness that MM is firmly based on a third, and equally important, pillar: Systems Biomedicine. Currently, this term denotes multilevel, hierarchical models integrating key factors at the molecular, cellular, tissue, through phenotype levels, analyzed to reveal the global behavior of the biological process under consideration. It becomes increasingly evident that the tools to construct such complex models include, not only bioinformatics and modern applied statistics, as is unanimously agreed, but also other interdisciplinary fields of science, notably, Mathematical Oncology, Systems Biology and Theoretical Biophysics.

About the authors

Alberto d’Onofrio is principal investigator in Systems Biomedicine at the European Institute of Oncology. His research interests focus on the application of mathematical and theoretical physics methodologies to study tumor biology, and the spread of infectious diseases. Webpage: http://www.ifom-ieo-campus.it/research/donofrio.php

Paola Cerrai is researcher at the Department of Mathematics of Pisa University, where she lectures in Mathematics and Statistics at the faculty of Biology. Her research interests focus on Mathematical Biology and Medicine. In particular: population dynamics, motion of bacteria and, more recently, growth of tumours and their interactions with the Immune System. She is also interested in the process (and in the related difficulties) of learning probability and statistics. She is intensely active in promoting the interdisciplinary cultural dialogue by organizing conferences and seminars.

Alberto Gandolfi works at Istituto di analisi dei Sistemi e di Informatica.

Table of contents (20 chapters)

  • Combining Game Theory and Graph Theory to Model Interactions between Cells in the Tumor Microenvironment

    Csikász-Nagy, Attila (et al.)

    Pages 3-18

  • Growth as the Root of all Evil in Carcinomas: Synergy between pH Buffering and Anti-Angiogenesis Prevents Emergence of Hallmarks of Cancer

    Silva, Ariosto (et al.)

    Pages 19-34

  • Phase Transitions in Cancer

    Solé, Ricard V.

    Pages 35-51

  • Spatio-Temporal Modelling of Intracellular Signalling Pathways: Transcription Factors, Negative Feedback Systems and Oscillations

    Chaplain, Mark A. J. (et al.)

    Pages 55-82

  • Understanding Cell Fate Decisions by Identifying Crucial System Dynamics

    Fey, Dirk (et al.)

    Pages 83-104

Buy this book

eBook $109.00
price for USA (gross)
  • ISBN 978-88-470-2571-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.00
price for USA
  • ISBN 978-88-470-2570-7
  • Free shipping for individuals worldwide
  • Online orders shipping within 2-3 days.
Softcover $139.00
price for USA
  • ISBN 978-88-470-5617-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
New Challenges for Cancer Systems Biomedicine
Editors
  • Alberto D'Onofrio
  • Paola Cerrai
  • Alberto Gandolfi
Series Title
SEMA SIMAI Springer Series
Copyright
2012
Publisher
Springer-Verlag Mailand
Copyright Holder
Springer-Verlag Italia Srl.
eBook ISBN
978-88-470-2571-4
DOI
10.1007/978-88-470-2571-4
Hardcover ISBN
978-88-470-2570-7
Softcover ISBN
978-88-470-5617-6
Series ISSN
2199-3041
Edition Number
1
Number of Pages
XII, 400
Topics