Topics in Neuroscience

Magnetic Resonance Techniques in Clinical Trials in Multiple Sclerosis

Editors: Filippi, M., Grossmann, R.I., Comi, G. (Eds.)

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  • ISBN 978-88-470-2153-2
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  • Immediate eBook download after purchase
Softcover $129.00
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About this book

We have entered an exciting period in the study of multiple sclerosis and its treatment. Central to this progress has been the introduction of magnetic reso­ nance techniques. When Young and his colleagues published the first images of the brain in multiple sclerosis at the end of 1981, it was at once obvious that magnetic resonance imaging would playa major role in diagnosis. Intuitively one felt that it would also have a role in increasing our understanding of the pathogenesis of the disease and in monitoring treatment. And so it has proved. Important problems however remain, perhaps the most important of which at present is the weak predictive power of standard magnetic resonance ima­ ging methods in determining the possibility of progression of impairment and disability. Recently, there have been advances which promise to overcome some of these problems, but decisions about what approach to adopt in selecting patients for clinical trials and which techniques to use in monitoring treatment during their course are still difficult. In this book, Dr. Filippi and his colleagues have assembled an outstanding group of contributors whose work is central to the progress that is being made. The coverage of the issues involved in the use of magnetic resonance techniques in assessing therapeutic effect is comprehensive and, though the field is chan­ ging rapidly, the principles and much of the detail in the book are likely to have lasting value.

Table of contents (11 chapters)

  • Introduction

    Filippi, M. (et al.)

    Pages 1-2

  • Clinical and Paraclinical Outcomes for Treatment Trials in Multiple Sclerosis

    Comi, G. (et al.)

    Pages 3-20

  • The Use of Magnetic Resonance Imaging to Select Patients for Multiple Sclerosis Clinical Trials

    Simon, J. H.

    Pages 21-36

  • The Application of Magnetic Resonance Imaging to Phase II Trials in Multiple Sclerosis

    McFarland, H. F. (et al.)

    Pages 37-48

  • Magnetic Resonance Imaging Techniques to Monitor Phase III Treatment Trials

    Molyneux, P. D. (et al.)

    Pages 49-73

Buy this book

eBook $99.00
price for USA (gross)
  • ISBN 978-88-470-2153-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $129.00
price for USA
  • ISBN 978-88-470-2180-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Magnetic Resonance Techniques in Clinical Trials in Multiple Sclerosis
Editors
  • M. Filippi
  • R.I. Grossmann
  • G. Comi
Series Title
Topics in Neuroscience
Copyright
1999
Publisher
Springer-Verlag Mailand
Copyright Holder
Springer-Verlag Italia
eBook ISBN
978-88-470-2153-2
DOI
10.1007/978-88-470-2153-2
Softcover ISBN
978-88-470-2180-8
Edition Number
1
Number of Pages
XI, 192
Topics