Topics in Anaesthesia and Critical Care

Metabolism and Artificial Nutrition in the Critically Ill

Editors: Guarnieri, G., Iscra, F. (Eds.)

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About this book

The critically ill patient in intensive care may present with serious metabolic alterations caused directly by the illness or secondarily by complications (e.g. infections, organ failure or sepsis) developing within a few hours of hospitaliza­ tion or in the following days. Among the situations which maintain and further trigger rapidly evolving altered metabolism are complex hormonal reactions, particularly those of the hypothalamus-hypophysis-adrenal axis, and abnormal stimulation of the autonomic nervous system. In fact, the sympathetic nervous system is known to cause significant metabolic alterations. For example, a surgery patient afflicted by septic complications may become hypercatabolic and experience significant nitrogen loss; the altered protein metabolism may in turn heavily influence carbohydrate and lipid metabolism as well. Thus, it is apparent that for optimal care of patients with altered metabolic functions, further knowledge is necessary regarding the physiopathology of metabolism and the physiopathological mechanisms, which alter the consump­ tion of principal energy substrates. Many experimental and clinical studies have investigated the metabolic aspects of individual organs or organ systems. However, for a correct evaluation of such metabolic events, in addition to studying the roles of metabolic enzymes, active metabolites, and the glutathione system, it is interesting to consider the use of indirect calorimetry as a valid and important investigative technique. The critically ill patient with major alterations in nutritional status may require artificial nutritive support administered through either parenteral or enteral routes.

Table of contents (22 chapters)

  • Substrate metabolism in critical illness

    Wolfe, R. R.

    Pages 3-10

  • Measurement of the body composition

    Ryde, S. J. S.

    Pages 11-27

  • Energy and ATP: Costs and benefits

    Flatt, J. P.

    Pages 29-45

  • Indirect calorimetry in the critically ill: theoretical aspects and practical problems

    Brandi, L. S. (et al.)

    Pages 47-57

  • Hormonal response of the hypothalamo-pituitary-adrenal axis in injury

    Chiolero, R. (et al.)

    Pages 61-70

Buy this book

eBook $99.00
price for USA (gross)
  • ISBN 978-88-470-2901-9
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $129.00
price for USA
  • ISBN 978-88-470-0042-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Metabolism and Artificial Nutrition in the Critically Ill
Editors
  • G. Guarnieri
  • F. Iscra
Series Title
Topics in Anaesthesia and Critical Care
Copyright
1999
Publisher
Springer-Verlag Mailand
Copyright Holder
Springer-Verlag Italia
eBook ISBN
978-88-470-2901-9
DOI
10.1007/978-88-470-2901-9
Softcover ISBN
978-88-470-0042-1
Edition Number
1
Number of Pages
XIV, 237
Number of Illustrations and Tables
5 b/w illustrations
Topics