Perspectives in Cancer Prevention-Translational Cancer Research

Editors: Perumana, Sudhakaran, Oommen, V., Pillai, M. Radhakrishna (Eds.)

  • Includes risk factors of cancer and  prevention strategies
  • Evidence-based drug development
  • Includes information on natural products and cancer therapeutics​
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eBook $149.00
price for USA (gross)
  • ISBN 978-81-322-1533-2
  • Digitally watermarked, DRM-free
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  • Immediate eBook download after purchase
Hardcover $199.00
price for USA
  • ISBN 978-81-322-1532-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: October 6, 2016
  • ISBN 978-81-322-3481-4
  • Free shipping for individuals worldwide
About this book

Being a complex disease that affects millions of people world over, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory or population studies into clinical application to reduce incidence of cancer , morbidity and mortality. It is becoming increasingly evident that cancer is a preventable disease. The IVth International Symposium on Translational Cancer Research held in Udaipur, India in December 2011, discussed various aspects of the biological processes in cancer cells and approaches to cancer prevention. A few contributions from this meeting are presented in this book, providing an in depth analysis of data on cancer prevention and therapeutics. These contributions are either critical reviews or research reports. The topics discussed include evidence-based nutritional recommendations for cancer patients and survivors, risk factors such as stress, enrichment of tumour stem cells by anticancer drug treatment contributing to tumour recurrence and the mechanism of anticancer effects of various natural products. Chemosensitizing effect of curcumin, anti-cancer effect of products from neem, action of sulforaphane and cytotoxic effect of a number of novel synthetic coordination complexes of trace metals have been discussed. Novel molecular targets of angiogenesis and molecular basis of the gender bias to thyroid cancer have also been discussed . This book provides useful information on translational cancer research to clinicians and biomedical scientists.

About the authors

Prof. P .R Sudhakaran is a well-known biochemist who has made significant contribution in the area of vascular biology. His major areas of research include cell matrix interaction and cell signalling in both physiological and pathological conditions including atherosclerosis, angiogenesis and cancer. As Head of the Department of Biochemistry, University of Kerala Thiruvananthapuram, and the founder Dean of School of Biological Sciences, Central University of Kerala, Kasargod, India , he has contributed significantly to biochemical education in the country and is presently the Director, Kerala State Biotechnology Commission. Dr Sudhakaran has published over 130 original research articles in international journals and is a fellow of the National Academy of Medical Sciences (India).

Prof. M. Radhakrishna Pillai is a well-known cancer biologist, Director of the Rajiv Gandhi Centre for Biotechnology, National Research Institute of the Government of India in Thiruvananthapuram, Kerala . A fellow of both the Science and Medical academies of India and the Royal College of Pathologists, London, Professor Pillai has provided one of the most elaborate data bases of cellular and molecular processes occurring during epithelial tumor progression especially roles of human papilloma virus and apoptosis. His work on cellular manifestations of HPV infection particularly p53 gene inactivation, defective apoptosis and angiogenesis culminated in the description of a "condemned mucosa syndrome", which was well received in the scientific community. He has also demonstrated the existence of various HPV 16 subtypes showing how they are associated with various grades of cervical disease.

Prof. Oommen’s research contributions on comparative endocrinology in non-mammalian vertebrates led to establish identical pattern in these vertebrates as in homeotherms A new species (Gegeneophis primus) of caecilian and an extensive taxonomic revision of a hitherto poorly known rainforest caecilian species Ichthyophis longicephalus are his recent works. Scientists from Natural History Museum, London honored him by naming a caecilian after him (Ureaotyphlus oommeni). His research links with MD Anderson Cancer Center, USA in Cancer saw three International Symposia on Translational cancer Research . Dr .Oommen is active in science popularization as the President of Kerala Academy of Sciences. Currently, Prof. Oommen is the Chairman, Kerala State Biodiversity Board

Table of contents (13 chapters)

  • Nutrition in Cancer: Evidence-Based Nutrition Recommendations in Cancer Patients and Survivors

    Rashid, Anis

    Pages 1-7

  • Tumour Stem Cell Enrichment by Anticancer Drugs: A Potential Mechanism of Tumour Recurrence

    Kumar, T. R. Santhosh (et al.)

    Pages 9-19

  • Curcumin: A Potent Candidate to be Evaluated as a Chemosensitizer in Paclitaxel Chemotherapy Against Cervical Cancer

    Sreekanth, Chanickal N. (et al.)

    Pages 21-43

  • Azadirachta indica (Neem) and Neem Limonoids as Anticancer Agents: Molecular Mechanisms and Targets

    Nagini, Siddavaram (et al.)

    Pages 45-60

  • In Vitro Studies on the Antioxidant/Antigenotoxic Potential of Aqueous Fraction from Anthocephalus cadamba Bark

    Chandel, Madhu (et al.)

    Pages 61-72

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-81-322-1533-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.00
price for USA
  • ISBN 978-81-322-1532-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: October 6, 2016
  • ISBN 978-81-322-3481-4
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Perspectives in Cancer Prevention-Translational Cancer Research
Editors
  • V. Oommen
  • M. Radhakrishna Pillai
  • Sudhakaran Perumana
Copyright
2014
Publisher
Springer India
Copyright Holder
Springer India
eBook ISBN
978-81-322-1533-2
DOI
10.1007/978-81-322-1533-2
Hardcover ISBN
978-81-322-1532-5
Softcover ISBN
978-81-322-3481-4
Edition Number
1
Number of Pages
XII, 168
Number of Illustrations and Tables
29 b/w illustrations, 22 illustrations in colour
Topics