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Chronic Inflammation

Mechanisms and Regulation

Editors: Miyasaka, Masayuki, Takatsu, Kiyoshi (Eds.)

  • Provides the most up-to-date summary of cutting-edge research on chronic inflammation
  • Clarifies the molecular link between chronic inflammation and various diseases including cancer, cardiovascular diseases, and diabetes mellitus
  • Provides insights into early detection and therapeutic intervention in chronic inflammation
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eBook $189.00
price for USA (gross)
  • ISBN 978-4-431-56068-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA
  • ISBN 978-4-431-56066-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book provides readers with the most up-to-date information on cutting-edge research concerning chronic inflammation. We now know that when inflammation becomes chronic, it acts as a strong disease-promoting factor in a variety of disorders including arteriosclerosis, obesity, cancer, and Alzheimer disease. Chronic inflammation is hence called as the “silent killer”; it upsets the body’s homeostatic mechanism insidiously. In spite of these developments, we know very little about the mechanism underlying chronic inflammation. Particularly, we do not know precisely what induces chronic inflammation or what promotes its prolongation in a spatiotemporal framework. Neither do we have clear knowledge about how chronic inflammation destroys various tissues or how it predisposes individuals to many different diseases. To make the situation worse, we have no effective treatment against chronic inflammation. 

Since 2010, two major research programs (CREST and PRESTO) aimed at clarifying the mechanisms underlying chronic inflammation were launched in Japan, and investigators of different research areas with a brilliant track record were selected by their research proposals. Subsequently they have made their best efforts to answer the conundrum concerning chronic inflammation. This book is a compendium of such research efforts. In each chapter, the CREST- or PRESTO-funded researchers summarize their original work concerning mechanisms of induction, progression, or resolution underlying chronic inflammation. The most emphasized characteristic is the molecular aspect of chronic inflammation. The book thus presents the most recent progress made in the molecular understanding of chronic inflammation.


About the authors

Masayuki Miyasaka, MD, PhD

Specially-Appointed Professor, IPBS, Osaka University,

Professor Emeritus, Osaka University,

FiDiPro Professor, Academy of Finland,

JST-CREST “Chronic Inflammation” Research Supervisor

 

Kiyoshi Takatsu, PhD

Director, Toyama Prefectural Institute for Pharmaceutical Research,

Visiting Professor, University of Toyama,

Professor Emeritus, The University of Tokyo, 

JST-PRESTO “Chronic Inflammation” Research Supervisor

Table of contents (52 chapters)

  • Prostaglandins in Chronic Inflammation

    Aoki, Tomohiro (et al.)

    Pages 3-17

  • Cellular and Molecular Mechanisms of Chronic Inflammation-Associated Organ Fibrosis

    Tsukui, Tatsuya (et al.)

    Pages 19-36

  • Sema4A and Chronic Inflammation

    Ito, Daisuke (et al.)

    Pages 37-48

  • MicroRNAs in Chronic Inflammation

    Ito, Y. (et al.)

    Pages 49-61

  • Genetic Dissection of Autoinflammatory Syndrome

    Yasutomo, Koji

    Pages 63-75

Buy this book

eBook $189.00
price for USA (gross)
  • ISBN 978-4-431-56068-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA
  • ISBN 978-4-431-56066-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Chronic Inflammation
Book Subtitle
Mechanisms and Regulation
Editors
  • Masayuki Miyasaka
  • Kiyoshi Takatsu
Copyright
2016
Publisher
Springer Japan
Copyright Holder
Springer Japan
eBook ISBN
978-4-431-56068-5
DOI
10.1007/978-4-431-56068-5
Hardcover ISBN
978-4-431-56066-1
Edition Number
1
Number of Pages
XI, 702
Number of Illustrations and Tables
28 b/w illustrations, 139 illustrations in colour
Topics