Autoimmune Liver Diseases

Perspectives from Japan

Editors: Ohira, Hiromasa (Ed.)

  • Based on Japanese research findings in autoimmune liver diseases
  • Explains how Japanese patients with autoimmune hepatitis form a unique disease population as a result of their genetic background
  • Presents the latest findings in research and treatment of primary biliary cirrhosis patients, along with new pathological staging criteria
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eBook $119.00
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  • ISBN 978-4-431-54789-1
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Hardcover $159.00
price for USA
  • ISBN 978-4-431-54788-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $159.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: August 30, 2016
  • ISBN 978-4-431-56171-2
  • Free shipping for individuals worldwide
Rent the ebook  
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About this book

Autoimmune Liver Diseases summarizes the recent high-impact research and clinical findings obtained in Japan in the study and treatment of autoimmune liver diseases. Although these disorders are relatively rare, they are recognized as an important group of refractory liver diseases, the most common of which are autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC). The book therefore comprises two major sections, one dealing with AIH, the other with PBC.

AIH in Japanese patients creates a unique disease population, as its clinical features are different from those of Western patients resulting from the different genetic background of the two patient populations. Also, mouse models of neonatal thymectomy-PD-1 knockout mice, clinical analyses of acute hepatitis-like manifestations, and research findings on IgG4-related autoimmune hepatitis have been reported in Japan and are included in this book. A disease-susceptibility gene specific to Japanese PBC patients has also recently been discovered. Because of the relatively homogeneous population of Japan, analyses conducted with Japanese PBC patients have yielded findings that are highly relevant to the pathogenesis of the disease.

Furthermore, new pathological staging criteria, anti-gp210 antibodies and the basis they provide for improved accuracy of prognosis, treatment with bezafibrate, and the outcomes of living-donor liver transplantation are also presented here. This volume therefore serves as a useful resource not only for hepatologists, but also for researchers, clinical residents, and medical students both in Japan and in other countries.

Table of contents (21 chapters)

  • Pathogenesis of Autoimmune Hepatitis

    Takahashi, Hiroki

    Pages 3-20

  • Models of Autoimmune Hepatitis

    Watanabe, Norihiko (et al.)

    Pages 21-35

  • Epidemiology and Natural History in Japan

    Yoshizawa, Kaname (et al.)

    Pages 37-44

  • Histological Findings of Autoimmune Hepatitis

    Harada, Kenichi

    Pages 45-65

  • Diagnosis of Autoimmune Hepatitis

    Zeniya, Mikio

    Pages 67-81

Buy this book

eBook $119.00
price for USA (gross)
  • ISBN 978-4-431-54789-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $159.00
price for USA
  • ISBN 978-4-431-54788-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $159.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: August 30, 2016
  • ISBN 978-4-431-56171-2
  • Free shipping for individuals worldwide
Rent the ebook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Autoimmune Liver Diseases
Book Subtitle
Perspectives from Japan
Editors
  • Hiromasa Ohira
Copyright
2014
Publisher
Springer Japan
Copyright Holder
Springer Japan
eBook ISBN
978-4-431-54789-1
DOI
10.1007/978-4-431-54789-1
Hardcover ISBN
978-4-431-54788-4
Softcover ISBN
978-4-431-56171-2
Edition Number
1
Number of Pages
VIII, 305
Number of Illustrations and Tables
26 b/w illustrations, 44 illustrations in colour
Topics