Schwann Cell Development and Pathology

Editors: Sango, Kazunori, Yamauchi, Junji (Eds.)

  • Presents up-to-date topics utilizing cutting-edge techniques, such as newly developed spontaneously immortalized Schwann cell lines
  • Provides deep insights into Schwann cell biology in normal and pathological conditions
  • Contains high-quality immunofluorescence images and electron micrographs
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eBook $149.00
price for USA (gross)
  • ISBN 978-4-431-54764-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-4-431-54763-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-4-431-56370-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book presents recent topics on the development, differentiation, and myelination of Schwann cells, as well as pathological mechanisms and therapeutic approaches for peripheral neuropathies, such as Charcot–Marie–Tooth diseases, amyloid polyneuropathy, immune-mediated neuropathy and diabetic neuropathy. The rapid progress of molecular biological techniques in the last decades, especially for RNA techniques and gene modification technologies have allowed us to investigate the pathobiology of Schwann cells in vivo and in vitro. Studies combining recent stem cell biology with recent biotechnology, which is now closely linked to physicochemical fields, further explain how Schwann cell lineages develop a process that has long been thought to be very complicated in vivo. The findings contribute to the elucidation of fundamental mechanisms during development and under pathological conditions. We now know that these are closely tied to each other. This book also introduces unique coculture systems to reproduce the neuron–Schwann cell interplay during development, degeneration, and regeneration. Up-to-date research topics with high-quality immunofluorescence and electron micrographs introduced by young and energetic contributors are sure to arouse the readers' interest in Schwann cell biology. Discussion from the viewpoint of basic and clinical neuroscience makes the book educational for researchers, medical students and young clinicians.

Table of contents (10 chapters)

  • Introduction

    Sango, Kazunori (et al.)

    Pages 1-4

  • Recent Insights into Molecular Mechanisms That Control Growth Factor Receptor-Mediated Schwann Cell Morphological Changes During Development

    Miyamoto, Yuki (et al.)

    Pages 5-27

  • Membrane Skeleton in Schmidt–Lanterman Incisure in Schwann Cells of the Peripheral Nervous System

    Terada, Nobuo (et al.)

    Pages 29-45

  • Schwann Cell–Axon Interactions: The Molecular and Metabolic Link Between Schwann Cells and Axons

    Ohno, Nobuhiko (et al.)

    Pages 47-67

  • Schwann Cell-Dependent Regulation of Peripheral Nerve Injury and Repair

    Susuki, Keiichiro

    Pages 69-79

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-4-431-54764-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-4-431-54763-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-4-431-56370-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Schwann Cell Development and Pathology
Editors
  • Kazunori Sango
  • Junji Yamauchi
Copyright
2014
Publisher
Springer Japan
Copyright Holder
Springer Japan
eBook ISBN
978-4-431-54764-8
DOI
10.1007/978-4-431-54764-8
Hardcover ISBN
978-4-431-54763-1
Softcover ISBN
978-4-431-56370-9
Edition Number
1
Number of Pages
X, 174
Number of Illustrations and Tables
17 b/w illustrations, 22 illustrations in colour
Topics