Testicular Autoimmunity

A Cause of Male Infertility

Authors: Itoh, Masahiro

  • Addresses various aspects of testicular autoimmunity, from its biological background to recent research data
  • Covers not only the autopsy and biopsy data for humans, but also experimental data using model animals
  • Written by one of the most prominent researchers in this field, who has established new murine models of autoimmune orchitis
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Buy this book

eBook $149.00
price for USA (gross)
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: August 22, 2017
  • ISBN 978-4-431-54460-9
  • Digitally watermarked, DRM-free
  • Included format:
  • ebooks can be used on all reading devices
Hardcover $189.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: July 25, 2017
  • ISBN 978-4-431-54459-3
  • Free shipping for individuals worldwide
About this book

This book addresses various aspects of testicular autoimmunity. It has long been suspected that testicular autoimmunity could be one of the causes of idiopathic male infertility. However, it is very difficult to estimate the incidence of testicular autoimmunity in men, as most male patients first realize they are infertile when they start trying to conceive a child, and there is a possibility that their testes may already exhibit the end stage of testicular autoimmunity, in which lymphocytic inflammation and immunoglobulin deposition in their testes subsided long ago and only the spermatogenic disorder remains. Therefore, autopsy or biopsy for testicular tissues in men before the end stage of testicular autoimmunity and investigations using testicular autoimmunity model animals are needed to determine the epidemiology of testicular autoimmunity.
Accordingly, the book discusses “the immunological fragility of testis” with regard to male infertility, reviewing autopsy data in men and presenting experimental data using murine models of autoimmune orchitis that has been induced by immunizing with viable syngeneic testicular germ cells alone. Testicular autoimmunity in animals is also discussed. 

In summary, the book provides a wealth of valuable information, not only for researchers who are interested in immunologic male infertility, but also for clinical professionals who treat these patients at hospitals.

About the authors

Dr. Masahiro Itoh obtained PfD degree in Division of Medicine, Kagawa University, in 1987. he started his carrier as an assistant professor at Kagawa University, and promoted to full Professor in 2001, at Tokyo Medical University. He is one of the top scientists in Japan and well-known as he succeeded in making new murine models of autoimmune orchitis.

Buy this book

eBook $149.00
price for USA (gross)
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: August 22, 2017
  • ISBN 978-4-431-54460-9
  • Digitally watermarked, DRM-free
  • Included format:
  • ebooks can be used on all reading devices
Hardcover $189.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: July 25, 2017
  • ISBN 978-4-431-54459-3
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Testicular Autoimmunity
Book Subtitle
A Cause of Male Infertility
Authors
Copyright
2017
Publisher
Springer Japan
Copyright Holder
Springer Japan
eBook ISBN
978-4-431-54460-9
DOI
10.1007/978-4-431-54460-9
Hardcover ISBN
978-4-431-54459-3
Edition Number
1
Number of Pages
XVII, 232
Number of Illustrations and Tables
4 b/w illustrations, 50 illustrations in colour
Topics