A First Course in “In Silico Medicine”

Harnessing Biological Complexity

An Introduction to Computational Physiology

Authors: Nomura, Taishin, Asai, Yoshiyuki

  • The development of physiome and systems biology will change conventional medicine which has been based on experience and expectation into "predictive medicine"
  • This book aims to establish a seamless educational system for engineers and clinicians who play a key role as leaders in relevant fields
  • Coverage based on advanced knowledge in engineering, informatics, medicine and clinical practices
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eBook $99.00
price for USA (gross)
valid through November 5, 2017
  • ISBN 978-4-431-53880-6
  • Digitally watermarked, DRM-free
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  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $129.00
price for USA
valid through November 5, 2017
  • ISBN 978-4-431-53879-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the eBook  
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About this book

The challenge for the biosciences in the twenty-first century is to integrate genome sequencing information into a better understanding of biology, physiology, and human pathology. Such attempts at integration are moving the world toward a new generation of bioscience and bioengineering, where biological, physiological, and pathological information from humans and other living animals can be quantitatively described in silico across multiple scales of time and size and through diverse hierarchies of organization — from molecules to cells and organs, to individuals. To "harness" such complexity, international communities of integrative bioscientists and bioengineers aim to establish frameworks and information infrastructures for describing biological structures and physiological functions on multiple scales of time and space. This textbook includes a public platform to describe physiological functions using mathematical equations and guides the reader to perform mathematical modeling and computer simulations, to combine existing models as well as to create new models. Accessible to biologists, physiologists, and students of the sciences, with illustrative details provided when necessary, this book seeks to achieve a systematic way of harnessing biological complexity. Sharing the databases among communities worldwide will help to find comprehensive answers to all the important questions.

Table of contents (5 chapters)

  • Introduction

    Nomura, Taishin (et al.)

    Pages 1-9

  • Modeling Cellular Dynamics

    Nomura, Taishin (et al.)

    Pages 11-81

  • Dynamics of Cellular Networks

    Nomura, Taishin (et al.)

    Pages 83-124

  • Application of ISIDE to Create Models

    Nomura, Taishin (et al.)

    Pages 125-194

  • Key Concepts of insilicoML

    Nomura, Taishin (et al.)

    Pages 195-216

Buy this book

eBook $99.00
price for USA (gross)
valid through November 5, 2017
  • ISBN 978-4-431-53880-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $129.00
price for USA
valid through November 5, 2017
  • ISBN 978-4-431-53879-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the eBook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Harnessing Biological Complexity
Book Subtitle
An Introduction to Computational Physiology
Authors
Series Title
A First Course in “In Silico Medicine”
Series Volume
1
Copyright
2011
Publisher
Springer Japan
Copyright Holder
Springer Japan KK
eBook ISBN
978-4-431-53880-6
DOI
10.1007/978-4-431-53880-6
Softcover ISBN
978-4-431-53879-0
Edition Number
1
Number of Pages
X, 190
Topics