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Progress in Drug Research

Natural Compounds as Drugs, Volume II

Editors: Petersen, Frank, Amstutz, René (Eds.)

  • Highlights innovative opportunities in drug discovery
  • Overview of strategies and screening methods
  • Compilation of current applicable technology – making this a brilliant reference work
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Buy this book

eBook $249.00
price for USA (gross)
  • ISBN 978-3-7643-8595-8
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $319.00
price for USA
  • ISBN 978-3-7643-8594-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The use of drug substances derived from plants, fungi, bacteria, and marine organisms has a long tradition in medicine. Together with their derivatives, and synthetic compounds deduced from natural product precursors, they represent a major part of today's pharmaceutical market.

Within the fast developing discipline of molecular biology, natural products also play an important role as tool compounds in pathway screening and validation of target identification concepts. They provide innovative opportunities in drug discovery, leading to a detailed understanding of biological pathways and revealing the functions of involved enzymes or receptors.

This book highlights new trends and aspects in natural products research. It discusses the biodiversity-driven approaches which are now of eminent importance in natural products research, addressing the question why natural products display such a complex chemical information, what makes them often unique and what their characteristics are. Practical questions such as supply of natural substances and production optimization strategies are also covered.

Reviews

From the reviews:

“This second compilation highlights innovative trends in natural products research. … provide very diverging aspects from molecular biology to practical questions such as production optimization strategies. … This well-designed volume provides reviews of constant quality in the important field of modern drug research written by an international crew of experts. … Figures / schemes (numerous formulas) and tables are useful and well organized. … I recommend this book to anyone interested in modern drug research. It would best be suited for science and industry libraries.” (Eckart Eich, Economic Botany, Vol. 63 (4), 2009)

Table of contents (9 chapters)

  • Activation of fungal silent gene clusters: A new avenue to drug discovery

    Brakhage, Axel A. (et al.)

    Pages 1-12

  • Total synthesis studies on macrocyclic pipecolic acid natural products: FK506, the antascomicins and rapamycin

    Maddess, Matthew L. (et al.)

    Pages 13-186

  • Application of natural product-inspired diversity-oriented synthesis to drug discovery

    Marcaurelle, Lisa A. (et al.)

    Pages 187-216

  • Cheminformatics analysis of natural products: Lessons from nature inspiring the design of new drugs

    Ertl, Peter (et al.)

    Pages 217-235

  • Chemical-genetic approaches for exploring the mode of action of natural products

    Lopez, Andres (et al.)

    Pages 237-271

Buy this book

eBook $249.00
price for USA (gross)
  • ISBN 978-3-7643-8595-8
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $319.00
price for USA
  • ISBN 978-3-7643-8594-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Natural Compounds as Drugs, Volume II
Editors
  • Frank Petersen
  • René Amstutz
Series Title
Progress in Drug Research
Series Volume
66
Copyright
2008
Publisher
Birkhäuser Basel
Copyright Holder
Birkhäuser Basel
Distribution Rights
Distribution rights for India: CBS Publishers, New Delhi, India
eBook ISBN
978-3-7643-8595-8
DOI
10.1007/978-3-7643-8595-8
Hardcover ISBN
978-3-7643-8594-1
Series ISSN
0071-786X
Edition Number
1
Number of Pages
X, 428
Number of Illustrations and Tables
185 b/w illustrations, 27 illustrations in colour
Topics