Overview
- Excellent overview of new approaches for the treatment of cancer
- Covers a large range of molecular targets
- Discusses the potential for clinical application
Part of the book series: Progress in Drug Research (PDR, volume 63)
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Table of contents (11 chapters)
Keywords
About this book
There have been tremendous advances in our understanding of molecular and tumor biology during the past few years. In the field of cancer therapeutics, it is expected that cytotoxic drug approaches will be gradually replaced with treatments based on biological targeted approaches. Hopefully these new targeted therapies will significantly increase efficacy and lack the devastating and troublesome side effects elicited by cytotoxic chemotherapy.
This volume is the first book to cover the general topic of targeted cancer therapy. It presents a range of targets such as tumor angiogenesis, cell cycle control and cell signalling, COX-2, apoptosis/cell survival, invasion and metastasis and approaches like kinase inhibitors, antisense, and antibody-based therapeutics. The emphasis is on preclinical development, including target validation, development of biomarkers, strategies for combination approaches, and development of resistance. The particular challenges involved in translating these data to clinical application are discussed.
This volume should be of broad general interest to researchers and clinicians involved in cancer therapy as well as other scientists interested in current strategies for cancer treatment.
Editors and Affiliations
Bibliographic Information
Book Title: Advances in Targeted Cancer Therapy
Editors: Paul L. Herrling, Alex Matter, Richard M. Schultz
Series Title: Progress in Drug Research
DOI: https://doi.org/10.1007/3-7643-7414-4
Publisher: Birkhäuser Basel
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Birkhäuser Basel 2005
Hardcover ISBN: 978-3-7643-7174-6Published: 16 September 2005
eBook ISBN: 978-3-7643-7414-3Published: 24 January 2006
Series ISSN: 0071-786X
Series E-ISSN: 2297-4555
Edition Number: 1
Number of Pages: VII, 303
Topics: Cancer Research, Molecular Medicine