Experientia Supplementum

NPY Family of Peptides in Neurobiology, Cardiovascular and Metabolic Disorders: from Genes to Therapeutics

Editors: Zukowska, Zofia, Feuerstein, Giora Z. (Eds.)

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  • ISBN 978-3-7643-7417-4
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About this book

The NPY-family of peptides encompasses several groups of neurotransmitters and hormones, which exert diverse biological and pathological actions that bear on all major vital systems. This book is a unique compilation of the most recent breakthroughs in NPY/PYY neurobiology, cardiovascular and metabolic disorders. The identification of multiple receptors for the members of the NPY and PYY family of peptides provides new opportunities for discovery of specific NPY antagonists and agonists that have vast clinical potential. The recognition of the role of NPY in stimulation of food intake has already resulted in discovery of potent and selective NPY receptor Y-5 antagonists, which are in clinical development for obesity. NPY Y1 receptor antagonists are targeted for cardiovascular indications. Research into the multiple functions of NPY and its receptors in neurological and affective disorders is also actively pursued. The chapters in this book are written by internationally renowned experts with the objective to synthesize leading concepts and data in support for translational medicine.

The ideal complement to this volume is the book NPY Family of Peptides in Immune Disorders, Inflammation, Angiogenesis, and Cancer, recently published by the same editors in the Birkhäuser book series Progress in Inflammation Research. Both volumes together give a comprehensive overview of the NPY family of peptides.

 

Table of contents (5 chapters)

  • An overview of neuropeptide Y: pharmacology to molecular biology and receptor localization

    Yvan Dumont, Rémi Quirion

    Pages 7-33

  • Neuropeptide Y and the heart: implication for myocardial infarction and heart failure

    Giora Z. Feuerstein, Edward W. Lee

    Pages 113-122

  • Role of neuropeptide Y in the regulation of kidney function

    Joseph Winaver, Zaid Abassi

    Pages 123-132

  • Subjugation of hypothalamic NPY and cohorts with central leptin gene therapy alleviates dyslipidemia, insulin resistance, and obesity for life-time

    Satya P. Kalra, Pushpa S. Kalra

    Pages 157-169

  • NPY and extreme stress: lessons learned from posttraumatic stress disorder

    Mary Ann Dutton, Edward W. Lee, Zofia Zukowska

    Pages 213-222

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-3-7643-7417-4
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $299.00
price for USA
  • ISBN 978-3-7643-7155-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
NPY Family of Peptides in Neurobiology, Cardiovascular and Metabolic Disorders: from Genes to Therapeutics
Editors
  • Zofia Zukowska
  • Giora Z. Feuerstein
Series Title
Experientia Supplementum
Series Volume
95
Copyright
2006
Publisher
Birkhäuser Basel
Copyright Holder
Birkhäuser Basel
eBook ISBN
978-3-7643-7417-4
DOI
10.1007/3-7643-7417-9
Hardcover ISBN
978-3-7643-7155-5
Series ISSN
1023-294X
Edition Number
1
Number of Pages
X, 280
Topics